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One is lonely and three is a crowd: Two coppers are for methane oxidation

Title
One is lonely and three is a crowd: Two coppers are for methane oxidation
Authors
Himes R.A.Barnese K.Karlin K.D.
Ewha Authors
Kenneth D. Karlin
Issue Date
2010
Journal Title
Angewandte Chemie - International Edition
ISSN
1433-7851JCR Link
Citation
vol. 49, no. 38, pp. 6714 - 6716
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
What/where is the active site? The determination of the metal ion content and makeup of the bacterial membrane protein methane monooxygenase (pMMO) has an enigmatic research history, despite protein X-ray structures. A new study appears to settle the issue; the dicopper center facilitates oxidation of methane to methanol. However, the unusual activesite environment leaves many questions for future investigations on the relevant copper-dioxygen chemistry and biochemistry. (Figure Presented) © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
DOI
10.1002/anie.201003403
Appears in Collections:
일반대학원 > 바이오융합과학과 > Journal papers
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