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Acute myeloid leukemia associated with t(10;17)(p13-15;q12-21) and phagocytic activity by leukemic blasts: A clinical study and review of the literature

Title
Acute myeloid leukemia associated with t(10;17)(p13-15;q12-21) and phagocytic activity by leukemic blasts: A clinical study and review of the literature
Authors
Oh S.H.Park T.S.Cho S.Y.Kim M.J.Huh J.Kim B.Song S.A.Lee J.Y.Jun K.R.Shin J.H.Kim H.R.Lee J.N.
Ewha Authors
허정원
SCOPUS Author ID
허정원scopus
Issue Date
2010
Journal Title
Cancer Genetics and Cytogenetics
ISSN
0165-4608JCR Link
Citation
vol. 202, no. 1, pp. 43 - 46
Indexed
SCOPUS WOS scopus
Abstract
Translocation (10;17)(p13-15;q12-21) in acute leukemia is rarely reported in the literature. Here, we present both a novel t(10;17) case study and a review of relevant literature on t(10;17) in acute leukemia (10 cases). In summary, we came to the following preliminary conclusions: t(10;17) is associated with poorly differentiated acute leukemia subtype [90%; eight cases of acute myeloid leukemia (AML M0, M1) and one case of acute undifferentiated leukemia], phagocytic activity by blasts occurs (30%), and the survival time was short in three of the seven t(10;17) cases for whom follow-up data were available (median, 8 months). More clinical studies concerning the prognosis, treatment response, and survival of patients with t(10;17) are necessary. © 2010 Elsevier Inc.
DOI
10.1016/j.cancergencyto.2010.06.005
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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