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The causative organisms of bacterial meningitis in Korean children in 1996-2005

Title
The causative organisms of bacterial meningitis in Korean children in 1996-2005
Authors
Cho H.K.Lee H.Kang J.H.Kim K.N.Kim D.S.Kim Y.K.Kim J.S.Kim J.-H.Kim C.H.Kim H.M.Park S.-E.Oh S.H.Chung E.H.Cha S.H.Choi Y.Y.Hur J.K.Hong Y.J.Lee H.J.Kim K.-H.
Ewha Authors
김경효
SCOPUS Author ID
김경효scopus
Issue Date
2010
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934JCR Link
Citation
vol. 25, no. 6, pp. 895 - 899
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
Bacterial meningitis remains a serious cause of morbidity and mortality in childhood, despite the availability of effective vaccines against Haemophilus influenzae type b (Hib) or Streptococcus pneumoniae. The purpose of this study was to analyze data on bacterial meningitis cases in Korea from 1996 through 2005. The information of all hospitalized bacteria-proven meningitis cases was obtained from 17 university hospitals nationwide. A total of 402 cases were identified. Of these, 125 (29.9%) cases were neonates. Streptococcus agalactiae was the most common bacteria responsible for 99 (24.6%) of all cases regardless of age, followed by S. pneumoniae for 91 (22.6%) and H. influenzae for 67 (16.7%) patients. The common etiology beyond the neonatal period was S. pneumoniae for 91 (33.0%) followed by H. influenzae for 63 (22.8%) patients. The overall case fatality rate was 9.4%, which was similar with that in 1986-1995. In conclusion, S. agalactiae, S. pneumoniae and H. influenzae were important etiologic agents of bacterial meningitis in children in the last 10 yrs. It is required to establish the preventive strategy of the three bacteria. The nationwide epidemiologic study should be continued to evaluate immunization strategy and efficacy. © 2010 The Korean Academy of Medical Sciences.
DOI
10.3346/jkms.2010.25.6.895
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의학전문대학원 > 의학과 > Journal papers
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