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Korean Pediatric/Adolescent Lymphoma - Incidence and Pathologic Characteristics

Title
Korean Pediatric/Adolescent Lymphoma - Incidence and Pathologic Characteristics
Authors
Lee S.-S.Kim J.-M.Ko Y.-H.Huh J.Kang C.S.Kim C.W.Kang Y.K.Go J.H.Kim M.K.Kim W.-S.Kim Y.J.Kim H.-J.Kim H.K.Nam J.H.Moon H.B.Park C.-K.Park T.I.Oh Y.-H.Lee D.W.Lee J.S.Lee J.Lee H.Lim S.-C.Jang K.Y.Chang H.-K.Jeon Y.K.Jung H.R.Cho M.-S.Cha H.J.Choi S.J.Han J.H.Hong S.H.Kim I.
Ewha Authors
조민선
SCOPUS Author ID
조민선scopus
Issue Date
2010
Journal Title
Korean Journal of Pathology
ISSN
1738-1843JCR Link
Citation
vol. 44, no. 2, pp. 117 - 124
Indexed
SCOPUS WOS scopus
Abstract
Background: The Hematopathology Study Group of the Korean Society of Pathologists conducted a nation-wide retrospective analysis of Korean pediatric lymphoma, to provide pathologic data on pediatric/adolescent lymphoma subtypes and features. Methods: All lymphoma cases of all age groups were collected during a recent 2 year-period (2005-2006) from 32 institutes in Korea. Among 3,686 lymphoma patients, 142 who were age 18 or less were classified according to the World Health Organization (WHO) classification. Results: Among 142 pediatric/adolescent lymphoma patients, Hodgkin lymphoma accounted for 21 (14.8%) and non-Hodgkin lymphoma (NHL) for 121 (85.2%). Hodgkin lymphoma appears to be more common in the pediatric/adolescent age group than in the all-ages group (14.8% vs 4.4%). T- and natural killer cell-NHL was more common in the pediatric/adolescent age group than in the all ages group (46.3% vs 22%). The majority of Korean pediatric/adolescent NHL cases was composed of Burkitt lymphoma, T- or B-lymphoblastic lymphoma, anaplastic large-cell lymphoma, and diffuse large B-cell lymphoma. For lymphoma patients under the age of 6 years, most had B-lymphoblastic or Burkitt lymphoma, which commonly presented at extranodal sites. Conclusions: The distribution of lymphoma subtypes in the pediatric/adolescent age group is quite different from the distribution of adults, but it was quite similar to distribution in Western countries.
DOI
10.4132/KoreanJPathol.2010.44.2.117
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의학전문대학원 > 의학과 > Journal papers
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