Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 홍영미 | * |
dc.contributor.author | 조인호 | * |
dc.date.accessioned | 2016-08-28T12:08:42Z | - |
dc.date.available | 2016-08-28T12:08:42Z | - |
dc.date.issued | 2010 | * |
dc.identifier.issn | 0307-0565 | * |
dc.identifier.other | OAK-6202 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/220468 | - |
dc.description.abstract | Background: Although the human adenovirus-36 (Ad-36) has been associated with obesity and related lipid disorders in the United States, this association has yet to be identified in other countries. Therefore, we tried to determine whether Ad-36 is associated with obesity or lipid disorders in Korean schoolchildren.Method:A total of 318 Korean schoolchildren aged 6-15 years, who participated in the Ewha Womans University Obesity Research Study, were selected for a community-based cohort study. Non-obese and obese were defined as body mass index (BMI) 85th and 95th percentiles of the Korean reference BMI-for-age curves, respectively, according to International Obesity Task Force definitions. The cutoff points for lipid disorders were modified from the age-modified standards of the National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP) III metabolic syndrome criteria. The Ad-36 antibody was measured using a serum neutralization assay.Results:More obese participants than non-obese participants tested positive for the Ad-36 antibody (28.57 vs 13.56%, respectively; P0.0174). Within the obese group, the participants who tested positive for the Ad-36 antibody had higher levels of triglycerides (TG) and total cholesterol than those who tested negative for the Ad-36 antibody (P0.001). However, these associations were not present in the non-obese group. The unadjusted odds ratio (OR) for Ad-36 antibody positivity was greater in obese participants than non-obese participants (OR2.550, 95% confidence interval (CI): 1.154-5.633). However, this OR seemed to be nonsignificant when age, sex and lipid variables were included in the analysis (OR1.752, 95% CI: 0.763-4.020). The unadjusted OR for the elevated TG was significantly higher in participants who were Ad-36 antibody-positive than those who were Ad-36 antibody-negative (OR2.511, 95% CI: 1.448-4.353). This trend remained constant even after adjustment for age, sex and obesity (OR2.328, 95% CI: 1.296-4.181).Conclusion:Ad-36 seems to be strongly associated with lipid disorders in Korean schoolchildren regardless of obesity. © 2010 Macmillan Publishers Limited. All rights reserved. | * |
dc.language | English | * |
dc.title | Association between human adenovirus-36 and lipid disorders in Korean schoolchildren | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 34 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 89 | * |
dc.relation.lastpage | 93 | * |
dc.relation.journaltitle | International Journal of Obesity | * |
dc.identifier.doi | 10.1038/ijo.2009.207 | * |
dc.identifier.wosid | WOS:000273519800013 | * |
dc.identifier.scopusid | 2-s2.0-74249117320 | * |
dc.author.google | Na H.-N. | * |
dc.author.google | Hong Y.-M. | * |
dc.author.google | Kim J. | * |
dc.author.google | Kim H.-K. | * |
dc.author.google | Jo I. | * |
dc.author.google | Nam J.-H. | * |
dc.contributor.scopusid | 홍영미(35210025100;57327441600;55841904000;56063366100) | * |
dc.contributor.scopusid | 조인호(26643129000;56663841900) | * |
dc.date.modifydate | 20240123112949 | * |