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Identification of antiadipogenic constituents of the rhizomes of Anemarrhena asphodeloides

Title
Identification of antiadipogenic constituents of the rhizomes of Anemarrhena asphodeloides
Authors
Ui J.Y.Ye S.L.Hana J.Jun L.Nam J.-W.Yoo J.L.Eun S.H.Lee J.-H.Dongho L.Sam S.K.Seo E.-K.
Ewha Authors
서은경황은숙
SCOPUS Author ID
서은경scopus; 황은숙scopus
Issue Date
2009
Journal Title
Journal of Natural Products
ISSN
0163-3864JCR Link
Citation
vol. 72, no. 10, pp. 1895 - 1898
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Three new phenolic compounds, (E)-4'-demethyl-6-methyleucomin (1), anemarcoumarin A (2), and anemarchalconyn (3), were isolated from an ethyl acetate extract of the rhizomes of Anemarrhena asphodeloides, together with seven known compounds (4-10). The structures of the new compounds (1-3) were determined on the basis of spectroscopic data interpretation. Compound 3 exhibited a potent inhibitory effect against the differentiation of preadipocyte 3T3-L1 cells with an IC 50 value of 5.3 μM. © 2009 American Chemical Society and American Society of Pharmacognosy.
DOI
10.1021/np900397f
Appears in Collections:
약학대학 > 약학과 > Journal papers
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