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Association of antioxidant vitamins and oxidative stress levels in pregnancy with infant growth during the first year of life

Title
Association of antioxidant vitamins and oxidative stress levels in pregnancy with infant growth during the first year of life
Authors
Hong J.Park E.A.Kim Y.-J.Lee H.Y.Park B.-H.Ha E.-H.Kong K.A.Park H.
Ewha Authors
하은희박은애김영주박혜숙이화영박보현
SCOPUS Author ID
하은희scopus; 박은애scopus; 김영주scopus; 박혜숙scopus; 이화영scopus; 박보현scopus
Issue Date
2008
Journal Title
Public Health Nutrition
ISSN
1368-9800JCR Link
Citation
vol. 11, no. 10, pp. 998 - 1005
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Objective: Whereas there are numerous reports in the literature relating the impact of maternal nutritional status on subsequent birth outcome, much less is known about the long-term impact on infant growth after birth. Therefore, we conducted a prospective cohort study to investigate the association of maternal micronutrient status (vitamins A, C and E, folate) and oxidative stress status in pregnancy with infant growth during the first year of life. Design: Prospective cohort study. Setting: Outpatient clinic of obstetrics, Ewha Womans University Hospital, Seoul, South Korea. Subjects and methods: Two groups were constructed for this study - the Ewha pregnancy cohort (n = 677) and the infant growth cohort comprising follow-up live newborns of all the recruited pregnant women (n = 317). Maternal serum vitamin and urinary oxidative stress levels were collected and infant weights and heights were measured at birth and at 6 and 12 months after birth. Results: Division of the subjects into folate-deficient and normal groups revealed that infant weight and height at 0, 6 and 12 months were adversely affected by folate deficiency. High maternal vitamin C was associated with increased infant weight and height at birth and after birth. Conclusion: Our findings indicate the importance of preventing folate deficiency and supplementing vitamin C during pregnancy. © The Authors 2007.
DOI
10.1017/S1368980007001322
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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