Hydrogen atom abstraction and hydride transfer reactions by iron(IV)-oxo porphyrins

Abstract

(Chemical Equation Presented) True identity revealed: The C-H bond activation of alkyl aromatics by synthetic iron(IV)-oxo porphyrin species and the hydride transfer of NADH analogues to them occur through H-atom abstraction and proton-coupled electron-transfer mechanisms, respectively. Mechanistic studies revealed that iron(IV)-oxo porphyrin π, not iron(IV)-oxo porphyrin pradical cations, are the true oxidant. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.