Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오세관 | * |
dc.contributor.author | 정재철 | * |
dc.date.accessioned | 2016-08-28T12:08:52Z | - |
dc.date.available | 2016-08-28T12:08:52Z | - |
dc.date.issued | 2008 | * |
dc.identifier.issn | 0932-0776 | * |
dc.identifier.other | OAK-4594 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/219955 | - |
dc.description.abstract | A convenient synthesis of 4-substituted 2-(3-hydroxy-2-oxo-1- phenethylpropylcarbamoyl)pyrrolidine-1-carboxylic acid benzyl esters 17 and 18 as new cysteine protease inhibitors is described. The synthetic key strategies involve the diazocarbonyl insertion reaction of N-Boc-L-homophenylalanine (1) by diazomethane, acetylation of the bromoketone 2 with sodium acetate, and condensation of acids 12, 14 with (3S)-3-amino-2-oxo-5-phenyl-pentyl acetate monohydrochloride (4) in good yield. © 2008 Verlag der Zeitschrift für Naturforschung. | * |
dc.language | English | * |
dc.title | A simple synthesis of 4-substituted 2-(3-hydroxy-2-oxo-1-phenethyl- propylcarbamoyl)pyrrolidine-1-carboxylic acid benzyl esters as novel cysteine protease inhibitors | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 63 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 210 | * |
dc.relation.lastpage | 216 | * |
dc.relation.journaltitle | Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences | * |
dc.identifier.wosid | WOS:000253003200015 | * |
dc.identifier.scopusid | 2-s2.0-39449118654 | * |
dc.author.google | Oh S. | * |
dc.author.google | Jung J.-C. | * |
dc.contributor.scopusid | 오세관(7404103757) | * |
dc.contributor.scopusid | 정재철(7402897187) | * |
dc.date.modifydate | 20240123112233 | * |