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Accelerated thrombotic occlusion of a medium-sized coronary aneurysm in Kawasaki disease by the inhibitory effect of ibuprofen on aspirin

Title
Accelerated thrombotic occlusion of a medium-sized coronary aneurysm in Kawasaki disease by the inhibitory effect of ibuprofen on aspirin
Authors
Sohn S.Kwon K.
Ewha Authors
손세정권기환
SCOPUS Author ID
손세정scopus; 권기환scopus
Issue Date
2008
Journal Title
Pediatric Cardiology
ISSN
0172-0643JCR Link
Citation
vol. 29, no. 1, pp. 153 - 156
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
The fate of coronary artery aneurysms (CAAs) caused by Kawasaki disease depends mainly on their initial size and shape. Small to medium-sized CAAs are known to regress to normal size or decrease in size, with a good outcome. A patient with Kawasaki disease is reported who had a medium-sized CAA prematurely occluded with thrombi during regression, resulting in myocardial ischemia. This event was probably due to simultaneous use of aspirin and ibuprofen. Thus, the concomitant use of ibuprofen should be avoided when aspirin is given as an antiplatelet agent because ibuprofen blocks the platelet inhibition induced by aspirin. © 2007 Springer Science+Business Media, LLC.
DOI
10.1007/s00246-007-9123-x
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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