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PM10 and pregnancy outcomes: A hospital-based cohort study of pregnant women in Seoul

Title
PM10 and pregnancy outcomes: A hospital-based cohort study of pregnant women in Seoul
Authors
Kim O.-J.Ha E.-H.Kim B.-M.Seo J.-H.Park H.-S.Jung W.-J.Lee B.-E.Suh Y.-J.Kim Y.-J.Lee J.-T.Kim H.Hong Y.-C.
Ewha Authors
하은희김영주박혜숙김병미
SCOPUS Author ID
하은희scopus; 김영주scopus; 박혜숙scopus; 김병미scopus
Issue Date
2007
Journal Title
Journal of Occupational and Environmental Medicine
ISSN
1076-2752JCR Link
Citation
vol. 49, no. 12, pp. 1394 - 1402
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
OBJECTIVE: The aim of this study was to evaluate the effects of PM10 on birth outcomes using a prospective cohort of pregnant women. METHODS: The multicenter prospective study was conducted in Korea from 2001 to 2004. To estimate the effects of PM10 exposure on birth outcomes, the logistic and linear regression model and the generalized additive model for nonlinear relationships were used. RESULTS: Stillbirths were affected by PM10 level during the third trimesters (OR = 1.10, 95% CI = 1.02-1.14), and birth defects were influenced by the PM10 exposure during the second trimesters (OR = 1.16, 95% CI = 1.00-1.34). Intrauterine growth retardation was affected by the first trimester's PM10 exposure. On the other hand, premature birth was affected by the PM10 exposure during the third trimester, and low-birth-weight births were affected by the PM10 level during entire trimesters of pregnancy. CONCLUSIONS: PM10 exposure during pregnancy may result in adverse birth outcomes with different critical periods. ©2007The American College of Occupational and Environmental Medicine.
DOI
10.1097/JOM.0b013e3181594859
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의학전문대학원 > 의학과 > Journal papers
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