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Platelet-enriched fibrin glue and platelet-rich plasma in the repair of bone defects adjacent to titanium dental implants

Title
Platelet-enriched fibrin glue and platelet-rich plasma in the repair of bone defects adjacent to titanium dental implants
Authors
You T.-M.Choi B.-H.Zhu S.-J.Jung J.-H.Lee S.-H.Huh J.-Y.Lee H.-J.Li J.
Ewha Authors
이승호
Issue Date
2007
Journal Title
International Journal of Oral and Maxillofacial Implants
ISSN
0882-2786JCR Link
Citation
vol. 22, no. 3, pp. 417 - 422
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Purpose: The aim of this study was to compare the effects of platelet-enriched fibrin glue and platelet-rich plasma (PRP) on the repair of bone defects adjacent to titanium dental implants. Materials and Methods: In 6 mongrel dogs, 3 screw-shaped titanium dental implants per dog were placed into the osteotomy sites in the tibia. Before implantation, a standardized gap (2.0 mm) was created between the implant surface and the surrounding bone walls. Six gaps were left empty (control group), 6 gaps were filled with autogenous particulate bone mixed with PRP (PRP group), and 6 gaps were filled with autogenous particulate bone mixed with platelet-enriched fibrin glue (fibrin glue group). Results: After 6 weeks, the bone-implant contact was 59.7% in the fibrin glue group, 29.2% in the PRP group, and 10.2% in the control defects; this difference was statistically significant (P < .05). Discussion and Conclusion: Greater bone-implant contact was achieved with platelet-enriched fibrin glue than with PRP. The results indicate that platelet-enriched fibrin glue can induce a stronger peri-implant bone reaction than PRP in the treatment of bone defects adjacent to titanium dental implants.
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의학전문대학원 > 의학과 > Journal papers
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