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Episodic diencephalic hypoperfusion in Kleine-Levin syndrome

Title
Episodic diencephalic hypoperfusion in Kleine-Levin syndrome
Authors
Hong S.B.Joo E.Y.Suk-Tae W.Lee J.Han S.J.Lee H.W.
Ewha Authors
이향운주은연
SCOPUS Author ID
이향운scopus
Issue Date
2006
Journal Title
Sleep
ISSN
0161-8105JCR Link
Citation
vol. 29, no. 8, pp. 1091 - 1093
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
A 22 year-old woman suffered from recurrent episodes of hypersomnia, apathy, and hyperphagia. The symptoms occurred 3 to 4 times per year, and each attack lasted 2 to 3 weeks. 99mTc-ethylcysteinate dimer brain single photon emission computed tomography (SPECT) was performed during symptomatic and asymptomatic periods. To localize brain regions with perfusion changes during symptomatic period, asymptomatic SPECT was subtracted from symptomatic SPECT. The subtracted SPECT showed significant hypoperfusion in the left hypothalamus, bilateral thalami, basal ganglia, bilateral medial and dorsolateral frontal regions, and left temporal lobe during the symptomatic period. These cerebral hypoperfusion areas support the diencephalic hypothesis and clinical symptoms of Kleine-Levin syndrome.
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의과대학 > 의학과 > Journal papers
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