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Bio-nanohybrids based on layered double hydroxide
- Bio-nanohybrids based on layered double hydroxide
- Choy J.-H.; Park M.; Oh J.-M.
- Ewha Authors
- SCOPUS Author ID
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- Journal Title
- Current Nanoscience
- Current Nanoscience vol. 2, no. 3, pp. 275 - 281
- SCIE; SCOPUS
- Document Type
- Layered double hydroxides (LDHs) with high anion exchange capacity have attracted particular attention in the fields of bio-hybrid nanomaterials due to their unique properties such as excellent biocompatibility, high affinity to carbonate anion, pH-dependent stability and high availability. To date, a variety of negatively charged biomolecules have been hybridized with LDHs to evolve into bio-LDH nanohybrids, including vitamins, drugs and DNA strands as well as simple organic acids. Bio-LDH nanohybrids can be readily prepared in a mild condition by coprecipitation, anion exchange or reconstruction. Their applications can be found in a wide range from the controlled release and delivery systems to biosensors and genetic molecular code system. In this review, special emphasis has been placed on DNA-LDH nanohybrids because DNA molecules are of great importance in many sciences and industrial fields. Their synthesis methods, characteristics and application potentials are reviewed briefly. © 2006 Bentham Science Publishers Ltd.
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