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Efficient synthesis of 2-substituted 2,3-dihydro-4-quinolones as potential intermediates for 2-substituted 1,2,3,4-tetrahydro-4-quinolone antitumor agents

Title
Efficient synthesis of 2-substituted 2,3-dihydro-4-quinolones as potential intermediates for 2-substituted 1,2,3,4-tetrahydro-4-quinolone antitumor agents
Authors
Choi S.Jung K.Ryu J.
Ewha Authors
최선류재상
SCOPUS Author ID
최선scopus; 류재상scopus
Issue Date
2006
Journal Title
Archives of Pharmacal Research
ISSN
0253-6269JCR Link
Citation
vol. 29, no. 5, pp. 369 - 374
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
An efficient method for the synthesis of optically active 2-substituted 2,3-dihydro-4-quinolones has been developed. The key features include the introduction of a chiral side chain and the construction of quinolone skeleton by Mitsunobu alkylation and hydroarylation, respectively.
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약학대학 > 약학과 > Journal papers
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