Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 신동해 | - |
dc.date.accessioned | 2016-08-28T11:08:03Z | - |
dc.date.available | 2016-08-28T11:08:03Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0961-8368 | - |
dc.identifier.other | OAK-3273 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/219685 | - |
dc.description.abstract | We have determined the crystal structure of the DUF16 domain of unknown function encoded by the gene MPN010 of Mycoplasma pneumoniae at 1.8 Å resolution. The crystal structure revealed that this domain is composed of two separated homotrimeric coiled-coils. The shorter one consists of 11 highly conserved residues. The sequence comprises noncanonical heptad repeats that induce a right-handed coiled-coil structure. The longer one is composed of approximately nine heptad repeats. In this coiled-coil structure, there are three distinguishable regions that confer unique structural properties compared with other known homotrimeric coiled-coils. The first part, containing one stutter, is an unusual phenylalanine-rich region that is not found in any other coiled-coil structures. The second part is a highly conserved glutamine-rich region, frequently found in other trimeric coiled-coil structures. The last part is composed of prototype heptad repeats. The phylogenetic analysis of the DUF16 family together with a secondary structure prediction shows that the DUF16 family can be classified into five subclasses according to N-terminal sequences. Based on the structural comparison with other coiled-coil structures, a probable molecular function of the DUF16 family is discussed. Copyright © 2006 The Protein Society. | - |
dc.language | English | - |
dc.title | Crystal structure of the DUF16 domain of MPN010 from Mycoplasma pneumoniae | - |
dc.type | Article | - |
dc.relation.issue | 4 | - |
dc.relation.volume | 15 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 921 | - |
dc.relation.lastpage | 928 | - |
dc.relation.journaltitle | Protein Science | - |
dc.identifier.doi | 10.1110/ps.051993506 | - |
dc.identifier.wosid | WOS:000236734200025 | - |
dc.identifier.scopusid | 2-s2.0-33645505710 | - |
dc.author.google | Dong H.S. | - |
dc.author.google | Kim J.-S. | - |
dc.author.google | Yokota H. | - |
dc.author.google | Kim R. | - |
dc.author.google | Kim S.-H. | - |
dc.contributor.scopusid | 신동해(57217374185) | - |
dc.date.modifydate | 20230208115524 | - |