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Mullerian adenosarcoma with sarcomatous overgrowth of the cervix presenting as cervical polyp: A case report and review of the literature

Title
Mullerian adenosarcoma with sarcomatous overgrowth of the cervix presenting as cervical polyp: A case report and review of the literature
Authors
Park H.M.Park M.H.Kim Y.J.Chun S.H.Ahn J.J.Kim C.I.Sung S.H.Han W.S.Kim S.C.
Ewha Authors
한운섭안정자전선희김승철김영주성순희박미혜
SCOPUS Author ID
한운섭scopusscopus; 안정자scopus; 전선희scopus; 김승철scopus; 김영주scopus; 성순희scopus; 박미혜scopus
Issue Date
2004
Journal Title
International Journal of Gynecological Cancer
ISSN
1048-891XJCR Link
Citation
vol. 14, no. 5, pp. 1024 - 1029
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
An aggressive variant of adenosarcoma, mullerian adenosarcoma with sarcomatous overgrowth (MASO) in the cervix is extremely rare. This variant contains obvious, high-grade sarcoma in addition to a low-grade form. In this report, we describe a case of MASO of the uterine cervix and review the clinical and pathological features of these tumors. The patient was a 37-year-old woman with a cervical polypoid mass, which was morphologically considered as a benign endocervical polyp. Microscopically, polypoid cervical mass showed diffuse and dense malignant spindle cell proliferation around the benign endocervical glands and also an area of markedly anaplastic and pleomorphic spindle cell proliferation, so called, sarcomatous overgrowth. Total abdominal hysterectomy and bilateral salpingo-oophorectomy with pelvic lymph node dissection were performed. The patient has been followed-up and neither chemotherapy nor other adjuvant therapies have been administered. At present, she has been clinically free of disease for 9 months since she received surgery. It is extremely rare that MASO of the uterine cervix is presented in premenopausal woman. Gynecologists and pathologists should be aware of the difficulties associated with a delay in the diagnosis of MASO when the tumor is present as a benign looking cervical polyp.
DOI
10.1111/j.1048-891X.2004.014546.x
Appears in Collections:
의과대학 > 의학과 > Journal papers
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