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A multi-center study for birth defect monitoring systems in Korea

Title
A multi-center study for birth defect monitoring systems in Korea
Authors
Yang J.-H.Kim Y.-J.Chung J.-H.Kim M.-Y.Ryu H.-M.Ahn H.-K.Han J.-Y.Yang S.-H.Kim A.Kim H.-S.Lee P.-J.Kim S.-S.Koh K.-S.Shin J.-C.Cho Y.-K.Yoon B.-H.
Ewha Authors
김영주
SCOPUS Author ID
김영주scopus
Issue Date
2004
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934JCR Link
Citation
vol. 19, no. 4, pp. 509 - 513
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
The aim of this study was to establish a multi-center birth defects monitoring system to evaluate the prevalence and the serial occurrence of birth defects in Korea. Ten medical centers participated in this program. A trained nurse collected relevant records from delivery units and pediatric clinics in participating hospitals on a monthly basis. We observed 1,537 cases of birth defects among 86,622 deliveries, which included live births and stillbirths. The prevalence of birth defects was 1.8%, and the sex distribution of the birth defect cases was 55.2% male and 41.6% female. The highest proportion of birth defects was in the cardiovascular system (17.5%), followed by birth defects involving in the genitourinary system (15.6%). Chromosomal anomalies were detected 30.0 per 10,000 births. Of these chromosomal anomalies, Down syndrome was most frequently observed. This study led to an establishment of a multi-center active monitoring system for birth defects. To better understand the serial occurrence of birth defects in Korea, it is necessary to increase the number of participating hospitals and to launch on a nation-wide multi-center study.
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의학전문대학원 > 의학과 > Journal papers
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