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A comparison of colour duplex ultrasonography after transurethral alprostadil and intracavernous alprostadil in the assessment of erectile dysfunction

Title
A comparison of colour duplex ultrasonography after transurethral alprostadil and intracavernous alprostadil in the assessment of erectile dysfunction
Authors
Ahn H.S.Lee S.W.Yoon S.J.Hann H.J.Hong J.M.
Ewha Authors
한후재
SCOPUS Author ID
한후재scopus
Issue Date
2004
Journal Title
Journal of International Medical Research
ISSN
0300-0605JCR Link
Citation
vol. 32, no. 3, pp. 317 - 323
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
This study aimed to investigate whether transurethral alprostadil could be used for the diagnosis of erictile dysfunction using colour duplex ultrasound. The ultrasonography results were compared after transurethral and intracavernous alprostadil administration in 20 patients with erectile dysfunction. There were no significant differences in the mean peak systolic velocities (PSVs) between the two routes of administration, but the mean end diastolic velocities (EDVs) showed significant differences, with patients treated with transurethral alprostadil having higher EDVs. Linear regression analysis of the PSVs reached following the two routes of administration showed a moderate relationship, but linear regression analysis of the EDVs showed no relationship. We concluded that transurethral alprostadil was an inappropriate vasoactive drug to use with colour duplex ultrasonography for the evaluation of patients with erectile dysfunction because it required a long scan time and it was less effective and less reliable than intracavernous alprostadil at stimulating complete corporeal smooth muscle relaxation.
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의학전문대학원 > 의학과 > Journal papers
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