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Treatment outcomes of uterine artery embolization and laparoscopic uterine artery ligation for uterine myoma

Title
Treatment outcomes of uterine artery embolization and laparoscopic uterine artery ligation for uterine myoma
Authors
Park K.-H.Kim J.-Y.Shin J.-S.Kwon J.-Y.Koo J.-S.Jeong K.-A.Cho N.-H.Bai S.-W.Lee B.-S.
Ewha Authors
정경아
SCOPUS Author ID
정경아scopus
Issue Date
2003
Journal Title
Yonsei Medical Journal
ISSN
0513-5796JCR Link
Citation
vol. 44, no. 4, pp. 694 - 702
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
In treating women with leiomyoma and who wish to preserve their uterus, laparoscopic uterine artery ligation or uterine artery embolization should be considered as possible options. This study was performed to evaluate the efficacy of laparoscopic uterine artery ligation and uterine artery embolization in treating uterine myoma. The treatment outcomes of 23 patients who underwent uterine artery embolization and 17 laparoscopic uterine artery ligation were evaluated. The uterine volume reduced 3 months after uterine artery embolization, but thereafter no significant changes were observed. On the other hand, the uterine volumes were only slightly reduced 3 months after laparoscopic uterine artery ligation, and slightly more reduced 6 months later. The average reduction in the case of laparoscopic uterine artery ligation was about 58.5%. After laparoscopic uterine artery ligation, 20% of the patients complained of vaginal spotting. Furthermore, the mechanism of volume reduction was evaluated using specimens obtained from a biopsy taken after each procedure. The results suggested that laparoscopic uterine artery ligation results mainly in physiologic cell death, that is apoptosis, whereas, the corresponding result is cell necrosis for uterine artery embolization. Uterine artery embolization and laparoscopic uterine artery ligation are both effective in relieving the symptoms caused by uterine myoma, and therefore both procedures can be used in place of hysterectomy or myomectomy.
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의학전문대학원 > 의학과 > Journal papers
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