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dc.contributor.author안정자-
dc.contributor.author우복희-
dc.contributor.author김승철-
dc.contributor.author문혜성-
dc.date.accessioned2016-08-28T11:08:26Z-
dc.date.available2016-08-28T11:08:26Z-
dc.date.issued2000-
dc.identifier.issn1048-891X-
dc.identifier.otherOAK-440-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/218640-
dc.description.abstractThe aim of this study was to determine the value of the measurement of serum VEGF and TGF-β1 levels in the diagnosis of cervical cancer and to see whether these levels decrease after treatment for cervical cancer. We measured serum VEGF and TGF-β1 levels through EIA in patients with CIN (n = 35), and cervical squamous cell cancer (n = 48). We also measured serum VEGF, TGF-β1, and SCC antigen levels before and after radiotherapy in 13 cervical squamous cell cancer patients. The sizes of the tumors in those patients were measured by a computer tomography scan or magnetic resonance imaging. The serum VEGF levels were different between CIN and cervical cancer groups (p < 0.1), and the serum TGF-β 1 levels in the cervical cancer group were lower than those in the other groups (P < 0.05). The serum VEGF levels were significantly related to the serum TGF-β 1 levels in the cervical cancer patients (P < 0.01). In the cervical cancer patients, the decrease in the circulating VEGF levels after receiving radiotherapy was related to the decrease in tumor size (P < 0.01). While the measurement of serum VEGF level is adjuvant in diagnosing cervical cancers, serial serum VEGF level measurements may find a clinical use in the follow-up of women treated for cervical cancer.-
dc.languageEnglish-
dc.titleConcentration of vascular endothelial growth factor (VEGF) and transforming growth factor β-1 (TGF-β1) in the serum of patients with cervical cancer: Prediction of response-
dc.typeArticle-
dc.relation.issue2-
dc.relation.volume10-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage151-
dc.relation.lastpage156-
dc.relation.journaltitleInternational Journal of Gynecological Cancer-
dc.identifier.doi10.1046/j.1525-1438.2000.00013.x-
dc.identifier.wosidWOS:000087345600010-
dc.identifier.scopusid2-s2.0-0034116456-
dc.author.googleMoon H.-S.-
dc.author.googleKim S.C.-
dc.author.googleAhn J.J.-
dc.author.googleWoo B.H.-
dc.contributor.scopusid안정자(7403019711)-
dc.contributor.scopusid우복희(7004853990;36939080900)-
dc.contributor.scopusid김승철(35264000100)-
dc.contributor.scopusid문혜성(14319143700)-
dc.date.modifydate20180403152604-
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의과대학 > 의학과 > Journal papers
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