Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남원우 | * |
dc.contributor.author | 이용민 | * |
dc.contributor.author | 박영준 | * |
dc.date.accessioned | 2016-08-28T11:08:57Z | - |
dc.date.available | 2016-08-28T11:08:57Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 0002-7863 | * |
dc.identifier.other | OAK-18974 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218351 | - |
dc.description.abstract | Metal nitrosyl complexes are key intermediates involved in many biological and physiological processes of nitric oxide (NO) activation by metalloproteins. In this study, we report the reactivities of mononuclear cobalt(III)-nitrosyl complexes bearing N-tetramethylated cyclam (TMC) ligands, [(14-TMC)Co-III(NO)](2+) and [(12-TMC)Co-III(NO)](2+), in NO-transfer and dioxygenation reactions. The Co(III)-nitrosyl complex bearing 14-TMC ligand, [(14-TMC)Co-III(NO)](2+), transfers the bound nitrosyl ligand to [(12-TMC)Co-II(NO)](2+) via a dissociative pathway,-[[(14-TMC)Co-III(NO)](2+) (14-TMC)Co center dot center dot center dot NO}(2+)}, thus affording [(12-TMC)Co-III(NO)](2+) and [(14-TMC)Co-II](2+) as products. The dissociation of NO from the [(14-TMC)COIII(NO)](2+) complex prior to NO-transfer is supported experimentally and theoretically. In contrast, the reverse reaction, which is the NO-transfer from [(12-TMC)Co-III(NO)](2+) to [(14-TMC)Co-II](2+), does not occur. In addition to the NO-transfer reaction, dioxygenation of [(14-TMC)Co-III(NO)](2+) by O-2 produces [(14-TMC)Co-II(NO3)](+), which possesses an O,O-chelated nitrato ligand and where, based on an experiment using O-18-labeled O-2, two of the three O-atoms in the [(14-TMC)Co-II(NO3)](+) product derive from O-2. The dioxygenation reaction is proposed to occur via a dissociative pathway, as proposed in the NO-transfer reaction, and via the formation of a Co (II) peroxynitrite intermediate, based on the observation of phenol ring nitration. In contrast, [(12-TMC)Co-III(NO)](2+) does not react with O-2. Thus, the present results demonstrate unambiguously that the NO-transfer/dioxygenation reactivity of the cobalt(III)-nitrosyl complexes bearing TMC ligands is significantly influenced by the ring size of the TMC ligands and/or the spin state of the cobalt ion. | * |
dc.language | English | * |
dc.publisher | AMER CHEMICAL SOC | * |
dc.title | Factors That Control the Reactivity of Cobalt(III)-Nitrosyl Complexes in Nitric Oxide Transfer and Dioxygenation Reactions: A Combined Experimental and Theoretical Investigation | * |
dc.type | Article | * |
dc.relation.issue | 24 | * |
dc.relation.volume | 138 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 7753 | * |
dc.relation.lastpage | 7762 | * |
dc.relation.journaltitle | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | * |
dc.identifier.doi | 10.1021/jacs.6b04040 | * |
dc.identifier.wosid | WOS:000378584600049 | * |
dc.identifier.scopusid | 2-s2.0-84976388598 | * |
dc.author.google | Kumar, Pankaj | * |
dc.author.google | Lee, Yong-Min | * |
dc.author.google | Hu, Lianrui | * |
dc.author.google | Chen, Jianwei | * |
dc.author.google | Park, Young Jun | * |
dc.author.google | Yao, Jiannian | * |
dc.author.google | Chen, Hui | * |
dc.author.google | Karlin, Kenneth D. | * |
dc.author.google | Nam, Wonwoo | * |
dc.contributor.scopusid | 남원우(7006569723) | * |
dc.contributor.scopusid | 이용민(36546331100;35233855500;57192113229) | * |
dc.contributor.scopusid | 박영준(57205877314) | * |
dc.date.modifydate | 20240130092654 | * |