Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 하은희 | * |
dc.contributor.author | 박혜숙 | * |
dc.date.accessioned | 2016-08-27T04:08:14Z | - |
dc.date.available | 2016-08-27T04:08:14Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 1011-8934 | * |
dc.identifier.issn | 1598-6357 | * |
dc.identifier.other | OAK-18631 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218234 | - |
dc.description.abstract | Our objective is to evaluate the relationships between prenatal maternal stress and depressive symptoms, respectively, and infant neurodevelopment at 6 months, adjusted for heavy metals and oxidative stress. This research is a part of a multi-center birth cohort study in South Korea. Information on stress and depressive symptoms was collected during the first trimester using Psychosocial Well-Being Index Short Form (PWI-SF) and Center for Epidemiological Studies Depression Scale (CES-D). The Korean Bayley Scales of Infant Development-II assessment (BSID-II), which includes the standardized mental development index (MDI) and psychomotor developmental index (PDI), and Korean Ages & Stages Questionnaires (K-ASQ) were applied to infants at six months of age. A higher index score indicates better development. Among 641 babies, 320 were female (50%). Maternal PWI >= 29 (vs. PWI <= 18) during early pregnancy was associated with a decrease in MDI scores of 5.37 points (P = 0.02) after adjusting for socioeconomic factors. Maternal CES-D >= 26 (vs. CES-D <= 10) during early pregnancy was associated with a decrease in MDI scores of 8.18 points (P = 0.01). The associations remained significant even after adjustment for lead, cadmium, and MDA levels (P < 0.05). However, no association was found between maternal PWI/CES-D and PDI score. No interaction was observed between stress and lead exposure. We found an inverse association between prenatal maternal stress and depressive symptoms, and MDI scores in 6-month-old infants after adjustment for prenatal lead exposure, which is known to affect cognitive function negatively. | * |
dc.language | English | * |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | * |
dc.subject | Antenatal Stress | * |
dc.subject | Cadmium | * |
dc.subject | Cognitive Development | * |
dc.subject | Depression | * |
dc.subject | Lead | * |
dc.subject | Malondialdehyde | * |
dc.subject | Oxidation | * |
dc.title | Maternal Stress and Depressive Symptoms and Infant Development at Six Months: the Mothers and Children's Environmental Health (MOCEH) Prospective Study | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 31 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 843 | * |
dc.relation.lastpage | 851 | * |
dc.relation.journaltitle | JOURNAL OF KOREAN MEDICAL SCIENCE | * |
dc.identifier.doi | 10.3346/jkms.2016.31.6.843 | * |
dc.identifier.wosid | WOS:000377169000003 | * |
dc.identifier.scopusid | 2-s2.0-84965056887 | * |
dc.author.google | Bhang, Soo-young | * |
dc.author.google | Ha, Eunhee | * |
dc.author.google | Park, Hyesook | * |
dc.author.google | Ha, Mina | * |
dc.author.google | Hong, Yun-Chul | * |
dc.author.google | Kim, Boong-Nyun | * |
dc.author.google | Lee, Soo-Jeong | * |
dc.author.google | Lee, Kyung Yeon | * |
dc.author.google | Kim, Ja Hyeong | * |
dc.author.google | Jeong, Joseph | * |
dc.author.google | Jeong, Kyoung Sook | * |
dc.author.google | Lee, Boeun | * |
dc.author.google | Kim, Yangho | * |
dc.contributor.scopusid | 하은희(7003615774) | * |
dc.contributor.scopusid | 박혜숙(57201862679;56148186100) | * |
dc.date.modifydate | 20240419135248 | * |