Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 류동열 | * |
dc.date.accessioned | 2016-08-27T04:08:08Z | - |
dc.date.available | 2016-08-27T04:08:08Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 0025-7974 | * |
dc.identifier.issn | 1536-5964 | * |
dc.identifier.other | OAK-18503 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218180 | - |
dc.description.abstract | Although icodextrin solution has been highlighted in the fluid management compared to glucose-based solutions, proof of a beneficial effect of icodextrin solution on residual renal function (RRF) is lacking. We conducted a multicenter prospective randomized controlled open-label trial to investigate whether icodextrin solution can preserve RRF. One hundred patients with urine volume >= 750 mL/day from 8 centers in Korea were randomly assigned to receive 1 exchange of icodextrin solution for a >= 8 hour-dwell time and 2 exchanges of 1.5% glucose-based biocompatible neutral pH solution or 1 exchange of >= 2.5% and 2 exchanges of 1.5% glucose-based biocompatible solutions. Using mixed-effects general linear models, we analyzed changes in residual glomerular filtration rate (GFR) and daily urine volume at 1 year. Forty-nine patients were assigned to the icodextrin group and 51 to the glucose solution group. During follow-up, the slope of the decline in residual GFR was -0.170mL/min/month/1.73m(2) in the icodextrin group, while it was -0.155mL/min/month/1.73m(2) in the glucose solution group (95% confidence interval [CI], -0.06 to 0.10; P=0.701). Daily urine volume decreased faster in the glucose solution group than in the icodextrin group (-31.02 vs -11.88mL per month; 95% CI, -35.85 to -2.44; P=0.025). Results were consistent when we analyzed using intention-to-treat and per protocol principles. There were no differences in fluid status, peritoneal ultrafiltration, and peritoneal transport between groups during follow-up. This study clearly showed that icodextrin solution preserves residual urine volume better than glucose solution. | * |
dc.language | English | * |
dc.publisher | LIPPINCOTT WILLIAMS & | * |
dc.publisher | WILKINS | * |
dc.title | Effect of Icodextrin Solution on the Preservation of Residual Renal Function in Peritoneal Dialysis Patients A Randomized Controlled Study | * |
dc.type | Article | * |
dc.relation.issue | 13 | * |
dc.relation.volume | 95 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | MEDICINE | * |
dc.identifier.doi | 10.1097/MD.0000000000002991 | * |
dc.identifier.wosid | WOS:000375256500001 | * |
dc.identifier.scopusid | 2-s2.0-84962665137 | * |
dc.author.google | Chang, Tae Ik | * |
dc.author.google | Ryu, Dong-Ryeol | * |
dc.author.google | Yoo, Tae-Hyun | * |
dc.author.google | Kim, Hyung Jong | * |
dc.author.google | Kang, Ea Wha | * |
dc.author.google | Kim, Hyunwook | * |
dc.author.google | Chang, Jae Hyun | * |
dc.author.google | Kim, Dong Ki | * |
dc.author.google | Moon, Sung Jin | * |
dc.author.google | Yoon, Soo Young | * |
dc.author.google | Han, Seung Hyeok|Yonsei Associate Network CHronic K | * |
dc.contributor.scopusid | 류동열(7103144218;56997547400;56669926200) | * |
dc.date.modifydate | 20240123102517 | * |