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Prediction of High-grade Vesicoureteral Reflux in Children Younger Than 2 Years Using Renal Sonography A Preliminary Study

Title
Prediction of High-grade Vesicoureteral Reflux in Children Younger Than 2 Years Using Renal Sonography A Preliminary Study
Authors
You, Sun KyoungKim, Jong ChunPark, Won HongLee, So MiCho, Hyun-Hae
Ewha Authors
조현혜
Issue Date
2016
Journal Title
JOURNAL OF ULTRASOUND IN MEDICINE
ISSN
0278-4297JCR Link1550-9613JCR Link
Citation
vol. 35, no. 4, pp. 761 - 765
Keywords
pediatric ultrasoundrenal sonographytechnetium Tc 99m-labeled dimercaptosuccinic acid scanningurinary tract infectionvesicoureteral refluxvoiding cystourethrography
Publisher
AMER INST ULTRASOUND MEDICINE
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Objectives-To investigate the predictive value of renal sonography for vesicoureteral reflux (VUR) and the efficacy of renal sonography, technetium Tc 99m-labeled dimercaptosuccinic acid (DMSA) scanning, and a combination of the two for VUR screening in children younger than 2 years with a first episode of febrile urinary tract infection. Methods-Thirty-eight patients younger than 2 years with a first febrile urinary tract infection were included in our study, which was conducted from April through October 2014. Each kidney was considered a separate renal unit. A retrospective review of clinical information and images (renal sonography, DMSA scanning, and voiding cystourethrography) was performed. Results-Of the 14 renal units (18.4%) with VUR, 4 (28.5%) had high-grade VUR. Among single findings, dilatation of the renal collecting system, wall thickening of the renal collecting system, and DMSA scans significantly predicted VUR (P=.038, .027, and .01, respectively). Dilatation was the most common single finding (46 of 76 renal units). The sensitivity values for dilatation, wall thickening, and DMSA scans were 85.7%, 64.2%, and 50.0%, and the negative predictive values were 93.3%, 89.7%, and 87.9%. Conclusions-The negative predictive values indicate that normal renal sonographic and DMSA findings can predict the absence of high-grade VUR. We propose that renal sonographic findings of wall thickening as well as dilatation of the renal collecting system should be considered predictive of high-grade VUR.
DOI
10.7863/ultra.15.04074
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의료원 > 의료원 > Journal papers
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