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Comparison of subfoveal choroidal thickness in healthy pregnancy and pre-eclampsia

Title
Comparison of subfoveal choroidal thickness in healthy pregnancy and pre-eclampsia
Authors
Kim, J. W.Park, M. H.Kim, Y. J.Kim, Y. T.
Ewha Authors
김윤택
SCOPUS Author ID
김윤택scopus
Issue Date
2016
Journal Title
EYE
ISSN
0950-222XJCR Link1476-5454JCR Link
Citation
vol. 30, no. 3, pp. 349 - 354
Publisher
NATURE PUBLISHING GROUP
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Purpose Pregnancy is a known predisposing factor for central serous chorioretinopathy (CSC). Choroidal thickness (CT) increases in patients with CSC. This study was designed to evaluate CT in pregnant women. Patients and methods This was a prospective study. Fourteen healthy pregnant women and seven patients with pre-eclampsia were included. Twenty-one normal subjects were also recruited. CT was measured using enhanced-depth imaging optical coherence tomography. Results The mean CT of normal subjects, healthy pregnant women and patients with pre-eclampsia were 264.95 +/- 21.03, 274.23 +/- 29.30 and 389.79 +/- 25.13 mu m, respectively (normal subjects vs healthy gravidas: P>0.05; normal subjects vs pre-eclampsia: P<0.001; healthy gravidas vs pre-eclampsia: P<0.001). CT decreased from 381.05 +/- 22.96 mu m to 335.17 +/- 9.97 mu m 1 week after delivery in patients with pre-eclampsia. Conclusions Pregnancy itself did not increase CT, whereas pre-eclampsia did appear to result in increased CT. This suggests that additional unknown factors induce hyperpermeability in pregnant women.
DOI
10.1038/eye.2015.215
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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