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The complexity of diagnosing postural orthostatic tachycardia syndrome: influence of the diurnal variability

Title
The complexity of diagnosing postural orthostatic tachycardia syndrome: influence of the diurnal variability
Authors
Moon, JangsupLee, Han SangByun, Jung-IckSunwoo, Jun-SangShin, Jung-WonLim, Jung-AhKim, Tae-JoonShin, Yong-WonLee, Keon-JooJeon, DaejongJung, Keun-HwaLee, Soon-TaeJung, Ki-YoungChu, KonLee, Sang Kun
Ewha Authors
문장섭
Issue Date
2016
Journal Title
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION
ISSN
1933-1711JCR Link1878-7436JCR Link
Citation
vol. 10, no. 3, pp. 263 - 270
Keywords
Postural tachycardia syndromeorthostatic tachycardiadiurnal variabilityorthostatic intoleranceorthostatic hypotension
Publisher
ELSEVIER SCIENCE INC
Indexed
SCIE; SCOPUS WOS scopus
Abstract
We investigated how the diagnosis of postural orthostatic tachycardia syndrome (POTS) would be changed due to diurnal variability in orthostatic tachycardia. The orthostatic vital sign test was administered to each patient twice, in the afternoon of the day of admission and the next morning (n = 113). Forty-six patients were diagnosed with POTS, and the remaining 67 patients were assigned to non-POTS group. Heart rate increments after standing were larger in the morning than in the afternoon in every group (all P < .001). Among the POTS patients, 82.6% fulfilled the diagnostic criteria for POTS in the morning and 52.2% in the afternoon. Most POTS group (65.2%) displayed normal result on single orthostatic vital sign test. Orthostatic intolerance symptoms were provoked in only 45.7% of the POTS patients, more frequently in the morning. In conclusion, diurnal variability in hemodynamic parameters and provoked symptoms significantly challenged the diagnosis of POTS. (C) 2016 American Society of Hypertension. All rights reserved.
DOI
10.1016/j.jash.2016.01.011
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연구기관 > 의과학연구소 > Journal papers
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