Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 박지만 | - |
dc.date.accessioned | 2016-08-27T04:08:53Z | - |
dc.date.available | 2016-08-27T04:08:53Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0882-2786 | - |
dc.identifier.issn | 1942-4434 | - |
dc.identifier.other | OAK-16452 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218029 | - |
dc.description.abstract | Purpose: A biochemical approach to implant surfaces can improve bone growth, resulting in desirable bone-implant interfaces. This study was conducted to identify the effect on osseointegration of direct coating of titanium (Ti) implants with poly(D, L-lactide-co-glycolide)(PLGA)/recombinant human bone morphogenetic 2 (rhBMP-2) submicron particles by electrospray. Materials and Methods: Anodized Ti implants were used as a control group, and implants coated with 80 mu L of PLGA/rhBMP-2 (50 mu g/mL rhBMP-2 per implant) submicron particles by electrospray were used as the experimental group in an in vivo rabbit tibia model. After 3 or 7 weeks of healing, specimens were obtained and prepared for histologic and histomorphometric analyses. Results: The implant surface coated with submicron PLGA/rhBMP-2 showed new bone growth in the apical direction earlier than control implants. In the experimental group at 3 weeks, the bone-to-implant contact ratio and bone area of the three best consecutive threads were significantly higher than those in the control group. However, there was no significant difference between groups at 7 weeks. Conclusion: Within the limitations of this study, the PLGA/rhBMP-2-coated implants facilitated osseointegration between bone and the Ti surface during the early healing phase. | - |
dc.language | English | - |
dc.publisher | QUINTESSENCE PUBLISHING CO INC | - |
dc.subject | anodized implant | - |
dc.subject | electrospray | - |
dc.subject | implant coatings | - |
dc.subject | osseointegration | - |
dc.subject | polylactic polyglycolic acid | - |
dc.subject | recombinant human bone morphogenetic protein 2 | - |
dc.subject | submicron particle | - |
dc.title | Biochemical Responses of Anodized Titanium Implants with a Poly(lactide-co-glycolide)/Bone Morphogenetic Protein-2 Submicron Particle Coating. Part 2: An In Vivo Study | - |
dc.type | Article | - |
dc.relation.issue | 4 | - |
dc.relation.volume | 30 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 754 | - |
dc.relation.lastpage | 760 | - |
dc.relation.journaltitle | INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS | - |
dc.identifier.wosid | WOS:000369629200002 | - |
dc.author.google | Yoo, Soo-Yeon | - |
dc.author.google | Kim, Seong-Kyun | - |
dc.author.google | Heo, Seong-Joo | - |
dc.author.google | Koak, Jai-Young | - |
dc.author.google | Lee, Joo-Hee | - |
dc.author.google | Park, Ji-Man | - |
dc.contributor.scopusid | 박지만(55839092400;56964592000) | - |
dc.date.modifydate | 20230120133940 | - |