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Risk of Advanced Colorectal Neoplasia According to the Number of High-Risk Findings at Index Colonoscopy: A Korean Association for the Study of Intestinal Disease (KASID) Study

Title
Risk of Advanced Colorectal Neoplasia According to the Number of High-Risk Findings at Index Colonoscopy: A Korean Association for the Study of Intestinal Disease (KASID) Study
Authors
Jung, Yoon SukPark, Dong IlKim, Won HeeEun, Chang SooPark, Soo-KyungKo, Bong MinSeo, Geom SeogCha, Jae MyungPark, Jae JunKim, Kyeong OkMoon, Chang MoJung, YunhoKim, Eun SooJeon, Seong RanLee, Chang Kyun
Ewha Authors
문창모
SCOPUS Author ID
문창모scopus
Issue Date
2016
Journal Title
DIGESTIVE DISEASES AND SCIENCES
ISSN
0163-2116JCR Link1573-2568JCR Link
Citation
vol. 61, no. 6, pp. 1661 - 1668
Keywords
ColonoscopyHigh-risk adenomaColorectal neoplasiaRecurrence
Publisher
SPRINGER
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Data regarding outcomes for patients with multiple findings for high-risk adenomas are scarce. To compare the risk for colorectal neoplasm (CRN) recurrence according to the number of high-risk findings. This was a retrospective and multicenter study. Patients who had one or more high-risk adenomas at the index colonoscopy and underwent follow-up colonoscopy 2.5 or more years after the index colonoscopy were included. The number of high-risk findings was defined as follows: number of adenomas larger than 1 cm + number of adenomas with HGD + number of adenomas with a villous component + existence (counted as 1) or nonexistence (counted as 0) of three or more adenomas. A total of 1646 patients were included, and the mean duration between index and follow-up colonoscopy was approximately 4 years. The cumulative incidence rate of recurrent advanced CRN in patients with three or more high-risk findings was higher than that in patients with one or two high-risk findings (p < 0.001). However, the difference in 3-year cumulative incidence rates of recurrent advanced CRN between the two groups was not great, although it was statistically significant (4.8 vs. 2.3 %, p = 0.039). A 3-year surveillance interval for patients with multiple high-risk findings, regardless of the number of high-risk findings, appears reasonable.
DOI
10.1007/s10620-016-4038-0
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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