Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이주호 | - |
dc.date.accessioned | 2016-08-27T04:08:43Z | - |
dc.date.available | 2016-08-27T04:08:43Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0003-4932 | - |
dc.identifier.issn | 1528-1140 | - |
dc.identifier.other | OAK-16240 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/217942 | - |
dc.description.abstract | Objective:To determine the safety of laparoscopy-assisted distal gastrectomy (LADG) compared with open distal gastrectomy (ODG) in patients with clinical stage I gastric cancer in Korea.Background:There is still a lack of large-scale, multicenter randomized trials regarding the safety of LADG.Methods:A large-scale, phase 3, multicenter, prospective randomized controlled trial was conducted. The primary end point was 5-year overall survival. Morbidity within 30 postoperative days and surgical mortality were compared to evaluate the safety of LADG as a secondary end pointResults:A total of 1416 patients were randomly assigned to the LADG group (n=705) or the ODG group (n=711) between February 1, 2006, and August 31, 2010, and 1384 patients were analyzed for modified intention-to-treat analysis (ITT) and 1256 were eligible for per protocol (PP) analysis (644 and 612, respectively). In the PP analysis, 6 patients (0.9%) needed open conversion in the LADG group. The overall complication rate was significantly lower in the LADG group (LADG vs ODG; 13.0% vs 19.9%, P=0.001). In detail, the wound complication rate of the LADG group was significantly lower than that of the ODG group (3.1% vs 7.7%, P<0.001). The major intra-abdominal complication (7.6% vs 10.3%, P=0.095) and mortality rates (0.6% vs 0.3%, P=0.687) were similar between the 2 groups. Modified ITT analysis showed similar results with PP analysis.Conclusions:LADG for patients with clinical stage I gastric cancer is safe and has a benefit of lower occurrence of wound complication compared with conventional ODG. | - |
dc.language | English | - |
dc.publisher | LIPPINCOTT WILLIAMS & | - |
dc.publisher | WILKINS | - |
dc.subject | complication | - |
dc.subject | laparoscopy | - |
dc.subject | morbidity | - |
dc.subject | mortality | - |
dc.subject | stomach neoplasm | - |
dc.title | Decreased Morbidity of Laparoscopic Distal Gastrectomy Compared With Open Distal Gastrectomy for Stage I Gastric Cancer Short-term Outcomes From a Multicenter Randomized Controlled Trial (KLASS-01) | - |
dc.type | Article | - |
dc.relation.issue | 1 | - |
dc.relation.volume | 263 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 28 | - |
dc.relation.lastpage | 35 | - |
dc.relation.journaltitle | ANNALS OF SURGERY | - |
dc.identifier.doi | 10.1097/SLA.0000000000001346 | - |
dc.identifier.wosid | WOS:000368004500008 | - |
dc.identifier.scopusid | 2-s2.0-84953839656 | - |
dc.author.google | Kim, Wook | - |
dc.author.google | Kim, Hyung-Ho | - |
dc.author.google | Han, Sang-Uk | - |
dc.author.google | Kim, Min-Chan | - |
dc.author.google | Hyung, Woo Jin | - |
dc.author.google | Ryu, Seung Wan | - |
dc.author.google | Cho, Gyu Seok | - |
dc.author.google | Kim, Chan Young | - |
dc.author.google | Yang, Han-Kwang | - |
dc.author.google | Park, Do Joong | - |
dc.author.google | Song, Kyo Young | - |
dc.author.google | Lee, Sang Il | - |
dc.author.google | Ryu, Seung Yub | - |
dc.author.google | Lee, Joo-Ho | - |
dc.author.google | Lee, Hyuk-Joon|Korean Laparo-endoscopic Gastroint | - |
dc.contributor.scopusid | 이주호(55689891300) | - |
dc.date.modifydate | 20230411113838 | - |