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Importance of Patients' Knowledge of Their Prescribed Medication in Improving Treatment Adherence in Inflammatory Bowel Disease

Title
Importance of Patients' Knowledge of Their Prescribed Medication in Improving Treatment Adherence in Inflammatory Bowel Disease
Authors
Tae, Chung HyunJung, Sung-AeMoon, Hye SungSeo, Jung-ASong, Hye KyungMoon, Chang MoKim, Seong-EunShim, Ki-NamJung, Hye-Kyung
Ewha Authors
정성애정혜경심기남김성은문창모태정현
SCOPUS Author ID
정성애scopus; 정혜경scopus; 심기남scopus; 김성은scopus; 문창모scopus; 태정현scopusscopus
Issue Date
2016
Journal Title
JOURNAL OF CLINICAL GASTROENTEROLOGY
ISSN
0192-0790JCR Link1539-2031JCR Link
Citation
vol. 50, no. 2, pp. 157 - 162
Keywords
adherenceinflammatory bowel diseasepatient medication knowledge
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Goals: To investigate the association between treatment nonadherence and patients' knowledge of the prescribed medication among individuals with inflammatory bowel disease (IBD), and evaluate the impact of nonadherence on relapse. Background: The patient's knowledge of the prescribed medication has been identified as an important predictor of treatment adherence in chronic diseases. However, this association has not been examined in IBD. Study: In this prospective study, at baseline, 138 patients with IBD completed a self-reported survey on demographic data, knowledge of the prescribed medication, and candidate factors related to the degree of treatment adherence. To investigate the impact of nonadherence among patients in remission, relapse was analyzed for 18 months after enrollment. Results: Nonadherence was observed in 50 (36.2%) of the 138 subjects. In multivariate analysis, nonadherence was significantly associated with younger age (less than 30 y) at participation [odds ratio (OR), 5.88; 95% confidence interval (CI), 1.51-22.94; P=0.011], longer intervals between outpatient clinic visits (>= 3 mo) (OR, 30.31; 95% CI, 3.06-300.17; P=0.004), and limited knowledge of the prescribed medication (OR, 5.61; 95% CI, 1.60-19.67; P=0.038). Nonadherent patients had a significantly greater risk of relapse of IBD than adherent patients (relative risk, 2.9; 95% CI, 2.25-3.79; P=0.045). Conclusion: Younger age, longer intervals between outpatient clinic visits, and limited knowledge of the prescribed medication tended to be associated with nonadherence to treatment, which consequently also affects the risk of relapse.
DOI
10.1097/MCG.0000000000000431
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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