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A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.

Title
A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.
Authors
Yang, InhoChoi, HyukjaeNam, Sang-JipKang, Heonjoong
Ewha Authors
남상집
SCOPUS Author ID
남상집scopus
Issue Date
2015
Journal Title
ARCHIVES OF PHARMACAL RESEARCH
ISSN
0253-6269JCR Link1976-3786JCR Link
Citation
vol. 38, no. 11, pp. 1970 - 1974
Keywords
SecosterolSpongeIrciniaAntibacterialMarine natural product
Publisher
PHARMACEUTICAL SOC KOREA
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
An intensive investigation of chemical components for Ircinia sp. led to the isolation of a new 9,11-secosterol. The chemical structure of this compound was elucidated based on the interpretation of NMR and MS spectroscopic data. The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25 mu g ml(-1), respectively.
DOI
10.1007/s12272-015-0620-9
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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