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The use of low-volume polyethylene glycol containing ascorbic acid versus 2 L of polyethylene glycol plus bisacodyl as bowel preparation for colonoscopy
- Title
- The use of low-volume polyethylene glycol containing ascorbic acid versus 2 L of polyethylene glycol plus bisacodyl as bowel preparation for colonoscopy
- Authors
- Tae, Chung Hyun; Jung, Sung-Ae; Na, Sun-Kyung; Song, Hye-Kyung; Moon, Chang Mo; Kim, Seong-Eun; Shim, Ki-Nam; Jung, Hye-Kyung; Moon, Il Hwan
- Ewha Authors
- 문일환; 정성애; 정혜경; 심기남; 김성은; 문창모; 태정현
- SCOPUS Author ID
- 문일환; 정성애; 정혜경; 심기남; 김성은; 문창모; 태정현
- Issue Date
- 2015
- Journal Title
- SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- ISSN
- 0036-5521
1502-7708
- Citation
- SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY vol. 50, no. 8, pp. 1039 - 1044
- Keywords
- ascorbic acid; bisacodyl; bowel preparation solutions; colonoscopy; polyethylene glycol
- Publisher
- TAYLOR &
FRANCIS LTD
- Indexed
- SCI; SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Objective. Low-volume polyethylene glycol (PEG) bowel preparations have been developed to improve compliance for colonoscopy. Our study aimed to compare the efficacy and tolerability of low-volume PEG containing ascorbic acid for colonoscopy against 2 L of PEG plus bisacodyl. Methods. We prospectively enrolled consecutive inpatients who had not undergone polypectomy at the index colonoscopy and were subsequently referred for polypectomy at our hospital. A total of 62 patients were randomized to receive either low-volume PEG containing ascorbic acid (n = 31) or 2 L of PEG plus bisacodyl (n = 31) as a split-dose regimen in inpatients. The efficacy of preparation was determined using the Ottawa Bowel Preparation Score (OBPS) and a 4-point scale. Adverse events, tolerability, and willingness were evaluated using a questionnaire. Results. Based on the OBPS and 4-point scale, we determined that the efficacy of low-volume PEG containing ascorbic acid was comparable to that of the 2 L of PEG plus bisacodyl (p = 0.071 for OBPS, p = 0.056 for the 4-point scale). Adverse events were comparable between the two groups (p = 1.000). A greater proportion of patients in the low-volume PEG containing ascorbic acid (90.6%) and the 2L of PEG plus bisacodyl (96.9%) were willing to repeat the same preparation for subsequent colonoscopy. Conclusion. Low-volume PEG containing ascorbic acid had comparable efficacy and tolerability to 2 L of PEG plus bisacodyl, when given as a split dose, for colonoscopy in inpatients. Split-dose low-volume PEG containing ascorbic acid is a good alternative for bowel preparation for colonoscopy in inpatients.
- DOI
- 10.3109/00365521.2014.1000961
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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