Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상화 | * |
dc.contributor.author | 이홍수 | * |
dc.contributor.author | 심경원 | * |
dc.contributor.author | 류동열 | * |
dc.contributor.author | 전혜진 | * |
dc.date.accessioned | 2016-08-27T04:08:29Z | - |
dc.date.available | 2016-08-27T04:08:29Z | - |
dc.date.issued | 2015 | * |
dc.identifier.issn | 0009-8981 | * |
dc.identifier.issn | 1873-3492 | * |
dc.identifier.other | OAK-14907 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/217205 | - |
dc.description.abstract | Background: Despite the previous studies showing the relationship between microalbuminuria and insulin resistance, longitudinal effect of insulin resistance on development of microalbuminuria is not clearly identified in non-diabetic population. Methods: One thousand six hundred three non-diabetic Korean men without microalbuminuria in 2005 had been followed up for the development of microalbuminuria until 2010. Microalbuminuria was evaluated by urine-albumin creatinine ration, and insulin resistance was evaluated by homeostasis model assessment of insulin resistance (HOMA-IR). Cox proportional hazards model was used to estimate the risk for microalbuminuria according to the tertile of HOMA-IR. Results: During 5465.8 person-y of average follow-up, microalbuminuria developed in 76 (4.7%) participants. Incidence of microalbuminuria increased in proportion to the level of HOMA-IR (tertile 1: 3.0%, tertile 2: 4.1%, tertile 3: 7.1%, P < 0.001). When the 1st tertile of HOMA-IR was set as reference, hazard ratios and 95% confidence interval were 1.15 (0.56-235) and 2.07 (1.05-4.09) for those in the 2nd and 3rd tertiles of HOMA-IR, even after adjusting multiple covariates, respectively (P for linear trend = 0.054). Conclusions: Increased insulin resistance was a predictor of microalbuminuria in Korean men. (C) 2015 Elsevier B.V. All rights reserved. | * |
dc.language | English | * |
dc.publisher | ELSEVIER SCIENCE BV | * |
dc.subject | Insulin resistance | * |
dc.subject | HOMA-IR | * |
dc.subject | Microalbuminuria | * |
dc.title | A cohort study of incident microalbuminuria in relation to HOMA-IR in Korean men | * |
dc.type | Article | * |
dc.relation.volume | 446 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 111 | * |
dc.relation.lastpage | 116 | * |
dc.relation.journaltitle | CLINICA CHIMICA ACTA | * |
dc.identifier.doi | 10.1016/j.cca.2015.03.043 | * |
dc.identifier.wosid | WOS:000356745600019 | * |
dc.identifier.scopusid | 2-s2.0-84928730018 | * |
dc.author.google | Park, Sung Keun | * |
dc.author.google | Chun, Hyejin | * |
dc.author.google | Ryoo, Jae-Hong | * |
dc.author.google | Lee, Sang Wha | * |
dc.author.google | Lee, Hong Soo | * |
dc.author.google | Shim, Kyung Won | * |
dc.author.google | Cho, Choo Yon | * |
dc.author.google | Ryu, Dorig-Ryeol | * |
dc.author.google | Ko, Taeg Su | * |
dc.author.google | Kim, Eugene | * |
dc.author.google | Park, Se-Jin | * |
dc.author.google | Park, Jai Hyung | * |
dc.author.google | Hong, Seok Jin | * |
dc.author.google | Hong, Hyun Pyo | * |
dc.contributor.scopusid | 이상화(55662653200;58067494900) | * |
dc.contributor.scopusid | 이홍수(54412527000) | * |
dc.contributor.scopusid | 심경원(8724567500) | * |
dc.contributor.scopusid | 류동열(7103144218;56997547400;56669926200) | * |
dc.contributor.scopusid | 전혜진(55650637900) | * |
dc.date.modifydate | 20240318132822 | * |