Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김범산 | * |
dc.contributor.author | 김예미 | * |
dc.date.accessioned | 2016-08-27T04:08:29Z | - |
dc.date.available | 2016-08-27T04:08:29Z | - |
dc.date.issued | 2015 | * |
dc.identifier.issn | 0914-7187 | * |
dc.identifier.issn | 1864-6433 | * |
dc.identifier.other | OAK-14905 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/217203 | - |
dc.description.abstract | Objectives This study investigated the prognostic value of preoperative breast-specific gamma imaging (BSGI) uptake measured by a semi-quantitative method in invasive ductal carcinoma (IDC). Methods One hundred and sixty-two women with IDC who underwent preoperative BSGI were retrospectively enrolled. The tumor-to-normal tissue ratio (TNR) was measured on BSGI and correlated with histologic prognostic factors. The prognostic impact of TNR was tested with regard to progression-free survival (PFS) and compared with established prognostic factors. Results High TNR was significantly correlated with tumor size > 2 cm (p < 0.001), high nuclear grade (p = 0.04), high histologic grade (p = 0.01), axillary node positivity (p = 0.04), ER negativity (p = 0.03), HER2 positivity (p = 0.01), and high MIB-1 index (p = 0.001). Among 162 patients, 14 experienced recurrence during mean follow-up time of 34.7 +/- 14.9 months. In Kaplan-Meier survival analyses, high TNR (p < 0.001), high nuclear grade (p = 0.02), high histologic grade (p = 0.007), ER/PR negativity (p = 0.003 and p < 0.001, respectively), HER2 positivity (p = 0.01), triple negativity (p = 0.02), and high MIB-1 index (p = 0.02) showed a significant relationship with poor prognosis. Among them, high TNR was an independent poor prognostic factor in a multivariate regression analysis (p = 0.01). Conclusion High BSGI uptake measured by a semi-quantitative method was correlated with diverse poor histologic prognostic factors and was an independent poor prognostic factor in invasive ductal cancer. | * |
dc.language | English | * |
dc.publisher | SPRINGER | * |
dc.subject | Breast-specific gamma imaging | * |
dc.subject | Tumor-to-normal tissue ratio | * |
dc.subject | Invasive ductal carcinoma | * |
dc.subject | Prognosis | * |
dc.title | Prognostic value of semi-quantitative tumor uptake on Tc-99m sestamibi breast-specific gamma imaging in invasive ductal breast cancer | * |
dc.type | Article | * |
dc.relation.issue | 7 | * |
dc.relation.volume | 29 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 553 | * |
dc.relation.lastpage | 560 | * |
dc.relation.journaltitle | ANNALS OF NUCLEAR MEDICINE | * |
dc.identifier.doi | 10.1007/s12149-015-0977-3 | * |
dc.identifier.wosid | WOS:000359014400001 | * |
dc.identifier.scopusid | 2-s2.0-84938745897 | * |
dc.author.google | Yoon, Hai-Jeon | * |
dc.author.google | Kim, Yemi | * |
dc.author.google | Chang, Kyu-Tae | * |
dc.author.google | Kim, Bom Sahn | * |
dc.contributor.scopusid | 김범산(35223582600) | * |
dc.contributor.scopusid | 김예미(36059180800) | * |
dc.date.modifydate | 20240123125716 | * |