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Role of shear-wave elastography (SWE) in complex cystic and solid breast lesions in comparison with conventional ultrasound
- Role of shear-wave elastography (SWE) in complex cystic and solid breast lesions in comparison with conventional ultrasound
- Lee, Bo Eun; Chung, Jin; Cha, Eun-Suk; Lee, Jee Eun; Kim, Jeoung Hyun
- Ewha Authors
- 이보은; 차은숙; 이지은; 정진; 김정현
- SCOPUS Author ID
- 차은숙; 이지은; 정진; 김정현
- Issue Date
- Journal Title
- EUROPEAN JOURNAL OF RADIOLOGY
- 0720-048X; 1872-7727
- vol. 84, no. 7, pp. 1236 - 1241
- Shear-wave; Elastography; Ultrasound; Breast; Cystic lesion
- ELSEVIER IRELAND LTD
- SCIE; SCOPUS
- Objective: To evaluate the additional role of shear-wave elastography (SWE) in differential diagnosis of complex cystic and solid breast lesions. Materials and methods: From January 2013 to November 2013, 140 complex cystic and solid breast lesions from 139 consecutive patients were performed ultrasound and SWE prior to biopsy. BI-RADS ultrasound final assessment and SWE parameters were recorded for each lesion. Histopathologic diagnosis was used as the reference standard. Results: Among the 140 lesions, 30 lesions (21.4%) were malignant. The mean maximum elasticity (Emax) of malignant lesions (184.3 kPa) was significantly higher than that of benign lesions (45.5 kPa) (P < 0.001). Homogeneity of elasticity and color pattern were significantly different from malignancy and benign lesions (P < 0.05). Emax with cutoff value at 108.5 kPa showed Az value of 0.968(95% CI, 0.932-0.985) with sensitivity of 86.7% and specificity of 97.3%. Using this cutoff value, false-positive rate was 2.7% and falsenegative rate was 13.3%. By applying an Emax value of 108.5 kPa or less as a criterion for downgrading BIRADS category 4a lesions to category 3 lesions, 103/123 (83.7%) lesions could be downgraded to category 3 lesions. Conclusion: Additional use of SWE could reduce unnecessary benign biopsies in complex cystic and solid breast lesions. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
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