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Symptom-oriented clinical detection versus routine imaging as a monitoring policy of relapse in patients with diffuse large B-cell lymphoma

Title
Symptom-oriented clinical detection versus routine imaging as a monitoring policy of relapse in patients with diffuse large B-cell lymphoma
Authors
Hong, JunshikKim, Ji HyunLee, Kyoung HwaAhn, Hee KyungPark, SanghuiSym, Sun JinPark, JinnyCho, Eun KyungShin, Dong BokLee, Jae Hoon
Ewha Authors
박상희
SCOPUS Author ID
박상희scopus
Issue Date
2014
Journal Title
LEUKEMIA & LYMPHOMA
ISSN
1042-8194JCR Link1029-2403JCR Link
Citation
vol. 55, no. 10, pp. 2312 - 2318
Keywords
Lymphomadiffuse large B-cell lymphomasurveillancemedical imaging
Publisher
INFORMA HEALTHCARE
Indexed
SCIE; SCOPUS WOS
Abstract
This study aimed at evaluating the role of routine imaging versus symptom-directed unplanned early outpatient department (OPD) visits in patients with diffuse large B-cell lymphoma (DLBCL) in complete remission (CR) by analyzing the patterns and outcomes of OPD visits for disease monitoring. Patients with DLBCL in CR after treatment in the rituximab era with any OPD monitoring visit were analyzed. A total of 856 OPD visits were recorded: 501 visits were with routine imaging, 322 were without routine imaging and 33 visits (3.9%) were unplanned early visits due to abnormal symptoms. Of the 106 analyzed patients, 15 experienced a relapse (median follow-up duration of 38.1 months). Routine imaging showed an unsatisfactory positive predictive value due to frequent false-positive visits, and a substantial number of patients with false-positive imaging underwent unnecessary biopsies or additional scans. Compared with planned OPD visits, unplanned early visits were highly related to relapse.
DOI
10.3109/10428194.2014.882505
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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