Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이승진 | - |
dc.date.accessioned | 2016-08-27T02:08:08Z | - |
dc.date.available | 2016-08-27T02:08:08Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0882-2786 | - |
dc.identifier.other | OAK-6487 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/216442 | - |
dc.description.abstract | Purpose: The purpose of this study was to evaluate the effect of basic fibroblast growth factor (bFGF) in combination with a biodegradable polymer coated onto titanium implants. The implants were inserted in rabbit tibiae, and bone growth was examined by histomorphometric analysis. Materials and Methods: Forty-eight threaded anodized implants were inserted into the tibiae of 12 rabbits. After 12 weeks of healing, an evaluation was made by light microscopy and computerized image analysis. A total of 56 anodized titanium implants were prepared as follows: group 1 was anodized under 300 V; group 2 was anodized then coated with 0.02 mL poly(lactide-co-glycolide) (PLGA) nanoparticles; group 3 was anodized then coated with 0.02 mL PLGA/bFGF nanoparticles (10 ng bFGF); and group 4 was anodized then coated with 0.2 mL PLGA/bFGF nanoparticles (100 ng bFGF). Results: Nanosized particles were observed on the coated implant surfaces. The mean diameter of the nanoparticles was 268.6 +/- 93.2 nm. The mean boneto-implant contact (BIC) percentage in group 4 (44.7%) was significantly greater than that seen in groups 1 (31.4%) and 2 (33.6%) (P < .05). Conclusions: The results of this preliminary study show that coating a titanium implant with PLGA incorporated with bFGF by electrospray may stimulate bone formation adjacent to the surface of an implant inserted in bone. INT J ORAL MAXILLOFAC IMPLANTS 2010; 25: 315-320 | - |
dc.language | English | - |
dc.publisher | QUINTESSENCE PUBLISHING CO INC | - |
dc.subject | anodized titanium | - |
dc.subject | electrospray | - |
dc.subject | fibroblast growth factor | - |
dc.subject | histomorphometric analysis | - |
dc.subject | poly(lactide-co-glycolide) | - |
dc.title | Osseointegration of Anodized Titanium Implants Coated with Poly(lactide-co-glycolide)/Basic Fibroblast Growth Factor by Electrospray | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 25 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 315 | - |
dc.relation.lastpage | 320 | - |
dc.relation.journaltitle | INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS | - |
dc.identifier.wosid | WOS:000276975600011 | - |
dc.author.google | Lee, Su Young | - |
dc.author.google | Koak, Jai Young | - |
dc.author.google | Heo, Seong Joo | - |
dc.author.google | Kim, Seong Kyun | - |
dc.author.google | Lee, Seung Jin | - |
dc.author.google | Nam, Seung Yeon | - |
dc.contributor.scopusid | 이승진(57196249292) | - |
dc.date.modifydate | 20230201093329 | - |