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A Case of Acantholytic Squamous Cell Carcinoma

Title
A Case of Acantholytic Squamous Cell Carcinoma
Authors
Lim, Ji-yeonDo, Mi-OkKim, Seong-hyunHahm, Jeong-HeeWhang, Kyu-Kwang
Ewha Authors
황규광
Issue Date
2008
Journal Title
ANNALS OF DERMATOLOGY
ISSN
1013-9087JCR Link
Citation
vol. 20, no. 4, pp. 267 - 270
Keywords
AcantholyticAdenoidSCCSkin
Publisher
KOREAN DERMATOLOGICAL ASSOC
Indexed
SCIE; SCOPUS; KCI WOS
Abstract
Acantholytic squamous cell carcinoma is a well-defined variant of squamous cell cancer in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular microscopic pattern. It usually presents as a nodule with various colors, and it is accompanied by scaling, crusting, and ulceration on the sun-exposed areas of older aged individuals. Histologically, the tumor consists of a nodular, epidermal-derived proliferation that forms island-like structures. At least focally or sometimes extensively, the tumor cells shows a loss of cohesion within the central gland-like or tubular spaces. This tumor resembles the structure of eccrine neoplasms, but it is negative for dPAS, CEA and mucicarmine and it is only positive for EMA and cytokeratins. Herein we report a case of acantholytic squamous cell carcinoma that occurred on the face of an 82-year-old woman.
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의과대학 > 의학과 > Journal papers
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