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A magnetic resonance-based seed localization method for 1-125 prostate implants

Title
A magnetic resonance-based seed localization method for 1-125 prostate implants
Authors
Lee, Rena J.Suh, HyunSukLee, Kyung-JaLim, SoomeKim, YookyungKim, SungkyuChoi, Jinho
Ewha Authors
이경자서현숙김유경임수미이레나
SCOPUS Author ID
이경자scopus; 김유경scopus; 임수미scopus; 이레나scopus
Issue Date
2007
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
ISSN
1011-8934JCR Link
Citation
vol. 22, pp. S129 - S133
Keywords
seed localizationprostateinterstitialbrachytherapymagnetic resonancecomputed tomography(125)l
Publisher
KOREAN ACAD MEDICAL SCIENCES
Indexed
SCI; SCIE; SCOPUS; KCI WOS
Abstract
This study was performed to develop and evaluate a semi-automatic seed localization algorithm from magnetic resonance (MR) images for interstitial prostate brachytherapy. The computerized tomography (CT) and MR images (3 mm-slice thickness) of six patients who had received real-time MR imaging-guided interstitial prostate brachytherapy were obtained. An automatic seed localization method was performed on CT images to obtain seed coordinates, and an algorithm for seed localization from MR images of the prostate was developed and tested. The resultant seed distributions from MR images were then compared to CT-derived distribution by matching the same seeds and calculating percent volume receiving 100% of the prescribed dose and the extent of the volume in 3-dimensions. The semiautomatic seed localization method made it possible to extract more than 90% of the seeds with either less than 8% of noises or 3% of missing seeds. The mean volume difference obtained from CT and MR receiving 100% of the prescribed dose was less than 3%. The maximum extent of the volume receiving the prescribed dose were 0.3, 0.6, and 0.2 cm in x, y, and z directions, respectively. These results indicate that the algorithm is very useful in identifying seeds from MR image for post-implant dosimety.
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의과대학 > 의학과 > Journal papers
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