View : 130 Download: 0

Clinical significance of small colorectal adenoma less than 10mm: The KASID study

Title
Clinical significance of small colorectal adenoma less than 10mm: The KASID study
Authors
Yoo, Tae WooPark, Dong IlKim, Young-HoKim, Hyun SooKim, Won HoKim, Tae IlKim, Hyo JongYang, Suk-KyunByeon, Jeong-SikLee, Moon SungJung, Il KwonChung, Moon KwanJung, Sung-AeJeen, Yoon TaeChoi, Jai HyunChoi, HwangHan, Dong SooSong, Jae Suk
Ewha Authors
정성애
SCOPUS Author ID
정성애scopus
Issue Date
2007
Journal Title
HEPATO-GASTROENTEROLOGY
ISSN
0172-6390JCR Link
Citation
vol. 54, no. 74, pp. 418 - 421
Keywords
small colorectal adenomaadvanced adenomacolorectal cancer
Publisher
H G E UPDATE MEDICAL PUBLISHING S A
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Background/Aims: Polypectomy is the current modality of choice to prevent benign colorectal adenoma from progressing to an invasive cancer. However, in cases of small colorectal adenoma, it remains unclear as to whether polypectomy is actually an effective treatment modality. We evaluated the clinical significance of polypectomy in cases of small colorectal adenomas, measuring less than 10mm. Methodology: All colonoscopies were performed at 11 Korean tertiary medical centers, between July 2003 and March 2004. A total of 5,996 colorectal adenomas were detected and divided into 5 groups according to their size (Group 1; 1-5mm, Group 2; 6-7mm, Group 3; 8-9mm, Group 4; 10-19mm, Group 5; more than 20mm). The term 'advanced adenoma' refers here to tubular adenomas with diameters of at least 10mm, or to tubulovillous, villous, or high-grade dysplasia, irrespective of size. 'Cancer' here is defined as the invasion of malignant cells beyond the muscularis mucosa. Results: As the sizes of the adenomas increased, the prevalence of advanced adenoma was also observed to increase. In Groups 2 and 3, the prevalence of tubulovillous or villous adenoma were higher than was expected (5.2% and 6.6%, p < 0.001). Interestingly enough, in Group 2, the prevalence of cancer was at least as high as in Group 4 (0.7% us. 0.5%, P < 0.001). Conclusions: In cases of small colorectal adenomas, measuring between 6 and 9mm, the prevalence of cancer was at least as high as that seen in the cases of colorectal adenomas measuring between 10 and 19mm. Therefore, small colorectal adenomas measuring between 6 and 9mm should not be ignored, in order to decrease the prevalence of colorectal cancer.
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE