Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 천은미 | - |
dc.contributor.author | 류연주 | - |
dc.date.accessioned | 2016-08-27T02:08:35Z | - |
dc.date.available | 2016-08-27T02:08:35Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0954-6111 | - |
dc.identifier.other | OAK-3870 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/216071 | - |
dc.description.abstract | The purpose of this study was to assess the role of bronchoalveolar lavage (BAL) in differentiating usual interstitial peumonia (UIP) from non-specific interstitial pneumonia (NSIP) and in predicting the prognosis in fibrotic idiopathic interstitial pneumonia (IIP). A retrospective review of 122 patients (age 58+8 years, 70 mate) with UIP (n = 87) and NSIP (n = 35) was carried out. Prior to surgical lung biopsy, all of them underwent BAL and high-resolution-computed tomography (HRCT) of the chest. Neutrophil count in BAL fluid was higher in UIP (7.0%) than NSIP (3.0%) (P = 0.027). In contrast, BAL lymphocyte count was significantly higher in NSIP (29.0%) than UIP (5.5%) (P < 0.0001). In 62 patients whose HRCT findings were atypical for UIP, BAL lymphocytosis was more frequently observed in NSIP (20/33) than UIP (4/29) (P < 0.001) and the absence of BAL lymphocytosis suggested a diagnosis of UIP rather than NSIP (odds ratio 12.7, P < 0.001). Pathologic diagnosis of NSIP was the only independent factor predicting a longer survival of our patients (median follow-up 21 months) (hazard ratio (HR) 0.035, P = 0.005). When NSIP was not included in the survival analysis, higher BAL lymphocyte count was the only independent predictor of a longer survival (HR 0.909, P = 0.029). BAL is an useful non-invasive tool. in fibrotic IIP, not only for excluding a variety of specific non-IIP diseases but also for narrowing the differential diagnosis and predicting the prognosis in the absence of the histopathologic diagnosis. (c) 2006 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.publisher | W B SAUNDERS CO LTD | - |
dc.subject | idiopathic interstitial pneumonia | - |
dc.subject | usual interstitial peumonia | - |
dc.subject | non-specific interstitial pneumonia | - |
dc.subject | bronchoalveolar lavage | - |
dc.title | Bronchoalveolar lavage in fibrotic idiopathic interstitial pneumonias | - |
dc.type | Article | - |
dc.relation.issue | 3 | - |
dc.relation.volume | 101 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 655 | - |
dc.relation.lastpage | 660 | - |
dc.relation.journaltitle | RESPIRATORY MEDICINE | - |
dc.identifier.doi | 10.1016/j.rmed.2006.06.003 | - |
dc.identifier.wosid | WOS:000244829500037 | - |
dc.author.google | Ryu, Yon Ju | - |
dc.author.google | Chung, Man Pyo | - |
dc.author.google | Han, Joungho | - |
dc.author.google | Kim, Tae Sung | - |
dc.author.google | Lee, Kyung Soo | - |
dc.author.google | Chun, Eun-Mi | - |
dc.author.google | Kyung, Sun Young | - |
dc.author.google | Jeong, Sung Hwan | - |
dc.author.google | Colby, Thomas V. | - |
dc.author.google | Kim, Hojoong | - |
dc.author.google | Kwon, O. Jung | - |
dc.contributor.scopusid | 천은미(13410658400) | - |
dc.contributor.scopusid | 류연주(8957498800) | - |
dc.date.modifydate | 20230210134735 | - |