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Cytotoxic constituents from the whole plant of Corydalis pallida

Title
Cytotoxic constituents from the whole plant of Corydalis pallida
Authors
Kim, HRMin, HYJeong, YHLee, SKLee, NSSeo, EK
Ewha Authors
이남숙이상국서은경
SCOPUS Author ID
이남숙scopus; 서은경scopus
Issue Date
2005
Journal Title
ARCHIVES OF PHARMACAL RESEARCH
ISSN
0253-6269JCR Link
Citation
vol. 28, no. 11, pp. 1224 - 1227
Keywords
Corydalis pallidaPapaveraceaeberberineN-trans-feruloylmethoxytyramineN-trans-feruloyltyraminecytotoxicity
Publisher
PHARMACEUTICAL SOCIETY KOREA
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
Here we report the cytotoxic activity of three known compounds isolated for the first time from Corydalis pallida (Papaveraceae). An isoquinoline alkaloid, berberine, exhibited cytototoxic activity against two human cancer cell lines, HT-1080 (human fibrosarcoma) and SNU-638 (human stomach adenocarcinoma), with lC(50) values of 3.2 and 3.4 mu g/mL, respectively. N-trans-feruloyltyramine and N-trans-feruloylmethoxytyramine were also isolated from this plant but were inactive.
DOI
10.1007/BF02978202
Appears in Collections:
자연과학대학 > 생명과학전공 > Journal papers
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