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A case of reactive plasmacytosis mimicking multiple myeloma in a patient with primary Sjogren's syndrome
- Title
- A case of reactive plasmacytosis mimicking multiple myeloma in a patient with primary Sjogren's syndrome
- Authors
- Lee, J; Chang, JE; Cho, YJ; Han, WS
- Ewha Authors
- 한운섭; 조영주; 이지수
- SCOPUS Author ID
- 한운섭; 조영주; 이지수
- Issue Date
- 2005
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- ISSN
- 1011-8934
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE vol. 20, no. 3, pp. 506 - 508
- Keywords
- Sjogren's syndrome; plasma cells; plasmacytosis; B cell differentiation
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Indexed
- SCI; SCIE; SCOPUS; KCI
- Document Type
- Article
- Abstract
- Primary Sjogren's syndrome (pSS) is a chronic autoimmune disease with well-documented association of lymphoid malignancies during the progress of the disease. Although several types of malignancy and pseudomalignancy have been reported in pSS, low-grade non-Hodgkin's lymphomas are the most frequently observed. Reactive plasmacytosis mimicking myeloma is a very rare condition in association with pSS. We describe a 72-yr-old woman with pSS who presented with hypergammaglobulinemia, and extensive bone marrow and lymph node plasmacytosis, which mimicked multiple myeloma. In this patient, there was an abnormal differentiation of memory B cells to plasma cells in the peripheral blood suggesting underlying pathogenetic mechanism for this condition.
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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