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A case of reactive plasmacytosis mimicking multiple myeloma in a patient with primary Sjogren's syndrome

Title
A case of reactive plasmacytosis mimicking multiple myeloma in a patient with primary Sjogren's syndrome
Authors
Lee, JChang, JECho, YJHan, WS
Ewha Authors
한운섭조영주이지수
SCOPUS Author ID
한운섭scopusscopus; 조영주scopus; 이지수scopus
Issue Date
2005
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
ISSN
1011-8934JCR Link
Citation
vol. 20, no. 3, pp. 506 - 508
Keywords
Sjogren's syndromeplasma cellsplasmacytosisB cell differentiation
Publisher
KOREAN ACAD MEDICAL SCIENCES
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
Primary Sjogren's syndrome (pSS) is a chronic autoimmune disease with well-documented association of lymphoid malignancies during the progress of the disease. Although several types of malignancy and pseudomalignancy have been reported in pSS, low-grade non-Hodgkin's lymphomas are the most frequently observed. Reactive plasmacytosis mimicking myeloma is a very rare condition in association with pSS. We describe a 72-yr-old woman with pSS who presented with hypergammaglobulinemia, and extensive bone marrow and lymph node plasmacytosis, which mimicked multiple myeloma. In this patient, there was an abnormal differentiation of memory B cells to plasma cells in the peripheral blood suggesting underlying pathogenetic mechanism for this condition.
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의학전문대학원 > 의학과 > Journal papers
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