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Improvement of image quality with beta-blocker premedication on ECG-gated 16-MDCT coronary angiography

Title
Improvement of image quality with beta-blocker premedication on ECG-gated 16-MDCT coronary angiography
Authors
Shim, SSKim, YLim, SM
Ewha Authors
김유경임수미심성신
SCOPUS Author ID
김유경scopus; 임수미scopus; 심성신scopus
Issue Date
2005
Journal Title
AMERICAN JOURNAL OF ROENTGENOLOGY
ISSN
0361-803XJCR Link
Citation
vol. 184, no. 2, pp. 649 - 654
Publisher
AMER ROENTGEN RAY SOC
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
OBJECTIVE. The objective of our study was to assess the effect of beta-blockers on image quality of ECG-gated 16-MDCT coronary angiography. MATERIALS AND METHODS. Coronary CT angiography was performed in two groups: group 1, 24 volunteers (mean age, 50 years; mean heart rate, 69 beats per minute [bpm]; range, 47-97 bpm); and group 2, 15 patients with current ischemic heart disease (mean age, 54 years; mean heart rate, 54 bpm; range, 48-69 bpm) who were premedicated with 20-40 mg of oral propranolol 1 hr before the study. CT scans were obtained on a 16-MDCT scanner with a 12 x 0.75 mm collimation and 420-msec rotation using nonionic contrast material (80 mL; injection rate, 4 ml/sec). Images were reconstructed at 30-80% of the cardiac cycle in increments of 5%. Image quality of the following eight coronary segments was assessed by two radiologists in consensus: left main coronary artery; proximal and middle segments of the left anterior descending (LAD) and left circumflex (LCX) coronary arteries; and the proximal, middle, and distal segments of the right coronary artery (RCA). Image quality was assessed, using a 5-point grading scale, as grades 1-5. Images assessed as grade 4 or 5 were considered to be of diagnostically acceptable quality. RESULTS. In group 1, grade 4 or 5 image quality was achieved for visualization of 92% of the left main coronary arteries; 96% of the proximal LAD coronary arteries; 88% of the middle LAD, proximal LCX, and middle LCX coronary arteries; 83% of the proximal RCAs; 58% of the middle RCAs; and 96% of the distal RCAs. In group 2, this level of image quality was achieved in 100% of the left main coronary arteries, proximal and middle LAD arteries, and proximal LCX arteries; 87% of the middle LCX arteries; and 93% of the proximal, middle, and distal RCAs. CONCLUSION. Reduction of heart rates with beta-blocker premedication improves the image quality of CT coronary angiography, especially in terms of the visualization of the right coronary artery.
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의학전문대학원 > 의학과 > Journal papers
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