View : 96 Download: 8

Plasma cell granuloma in cyclosporine-induced gingival overgrowth - A report of two cases with immurlohistochemical positivity of interleukin-6 and phospholipase C-gamma 1

Title
Plasma cell granuloma in cyclosporine-induced gingival overgrowth - A report of two cases with immurlohistochemical positivity of interleukin-6 and phospholipase C-gamma 1
Authors
Kim, SSEom, DHuh, JSung, LYChoi, IRyu, SHSuh, PGChung, SM
Ewha Authors
정성민
SCOPUS Author ID
정성민scopus
Issue Date
2002
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
ISSN
1011-8934JCR Link
Citation
vol. 17, no. 5, pp. 704 - 707
Keywords
cycosporinside effectgingival overgrowthplasma cellsinterleukin-6phospholipase C
Publisher
KOREAN ACAD MEDICAL SCIENCES
Indexed
SCI; SCIE; SCOPUS; KCI WOS
Abstract
We report two cases of gingival plasma cell granuloma in a 34-yr-old and 40-yrold two male renal transplant recipients with cyclosporine A (CsA)-induced gingival overgrowth (GO). Histologically, these lesions were composed of mature plasma cells, showing polyclonality for both lambda and kappa light chains and fibrovascular connective tissue stroma. In addition to the fact that CsA-induced plasma cell granuloma is rare, the salient features of our cases were the secretion of interleukin-6 and overexpression of phospholipase C-gamma1 of the tumor cells, which may explain the mechanisms of CsA-induced GO.
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
Plasma cell granuloma in cyclosporine-induced gingival overgrowth.pdf(206.95 kB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE