View : 549 Download: 184
Orientia tsutsugamushi inhibits apoptosis of macrophages by retarding intracellular calcium release
- Title
- Orientia tsutsugamushi inhibits apoptosis of macrophages by retarding intracellular calcium release
- Authors
- Kim, MK; Seong, SY; Seoh, JY; Han, TH; Song, HJ; Lee, JE; Shin, JH; Lim, BU; Kang, JS
- Ewha Authors
- 서주영
- SCOPUS Author ID
- 서주영
- Issue Date
- 2002
- Journal Title
- INFECTION AND IMMUNITY
- ISSN
- 0019-9567
- Citation
- INFECTION AND IMMUNITY vol. 70, no. 8, pp. 4692 - 4696
- Publisher
- AMER SOC MICROBIOLOGY
- Indexed
- SCI; SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Orientia tsutsugamushi shows both pro- and antiapoptotic activities in infected vertebrate cells. Apoptosis of THP-1 cells induced by beauvericin was inhibited by O. tsutsugamushi infection. Beauvericin-induced calcium redistribution was significantly reduced and retarded in cells infected with O. tsutsugamushi. Antiapoptotic activities of O. tsutsugamushi in infected cells are most probably due to inhibition of the increase in the cytosolic calcium concentration.
- DOI
- 10.1128/IAI.70.8.4692-4696.2002
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
-
Orientia tsutsugamushi inhibits apoptosis of macrophages by retarding intracellular calcium release.pdf(1.04 MB)
Download
- Export
- RIS (EndNote)
- XLS (Excel)
- XML