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Non-tuberculous mycobacterial keratitis at the interface after laser in situ keratomileusis

Title
Non-tuberculous mycobacterial keratitis at the interface after laser in situ keratomileusis
Authors
Seo, KYLee, JBLee, KKim, MJChoi, KRKim, EK
Ewha Authors
최규룡
SCOPUS Author ID
최규룡scopus
Issue Date
2002
Journal Title
JOURNAL OF REFRACTIVE SURGERY
ISSN
1081-597XJCR Link
Citation
vol. 18, no. 1, pp. 81 - 85
Publisher
SLACK INC
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
PURPOSE: To describe two cases of bacterial keratitis with atypical mycobacteria after laser in situ keratomileusis (LASIK). METHODS: Two cases of non-tuberculous mycobacterial keratitis occurred in the interface between the stromal bed and flap, 20 days and 14 days after LASIK. The keratitis progressed slowly and worsened after attempts were made to remove the colonies. Mycobacterium fortuitum was confirmed 2 months after initial presentation following culture of the excised flap tissue in one case, and Mycobacterium chelonae was identified by culture of removed material and by RT-PCR with primers in the other case. The patients were treated medically and by surgical flap removal. RESULTS: In the first case, the keratitis was controlled only after removal of the partially melted flap and intensive medical treatment. In the second case, the lesion cleared after 2 months of antibiotics, but after tapering of antibiotics, the infiltrate progressed. Eventually, the keratitis was controlled after removal of the flap. CONCLUSIONS: Non-tuberculous Mycobacterium should be considered as one of the causes of keratitis when presenting as white colonies in the lamellar bed after LASIK. Treatment for 2 months may not be enough to eradicate the infection and excision of the flap may be necessary.
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의과대학 > 의학과 > Journal papers
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