Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 신명헌 | - |
dc.date.accessioned | 2016-08-27T02:08:31Z | - |
dc.date.available | 2016-08-27T02:08:31Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.other | OAK-629 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/215400 | - |
dc.description.abstract | The in vitro activity of 2,2'-dipyridyl, an iron-chelator, against clinical isolates of Trichomonas vaginalis. Candida albicans, and Gardnerella vaginalis was evaluated and compared with those of four other vaginal suppositories. ornidazole, clotrimazole, povidone-iodine. and Cenacert(R) (Methylbenzethonium Chloride mixed with 9-aminoacrydine undecylenate and hydrochloric acid N-myristyl-3-hydroxy butyl amine). The 2.2'-dipyridyl killed T. vaginalis and G. vaginalis at concentrations of 410 mug/ml and 205 mug/ml, respectively, however, this agent was less active against C. albicans (80% of which was inhibited at 410 mug/ml). The inhibition of these three pathogens by 2,2'-dipyridyl was similar to clotrimazole. In addition, the effect of 2,2'-dipyridyl on the ultrastructure of T. vaginalis. C, albicans, and G. vaginalis was examined. Transmission electron microscopy indicated that 2,2'-dipyridyl induced modifications of the cellular contents and cell envelope concomitant with the degradation of the three pathogens. These results suggest that 2.2'-dipyridyl has an inhibitory effect on C. albicans and G. vaginalis, as well as T. vaginalis. | - |
dc.language | English | - |
dc.publisher | KOREAN SOC APPLIED MICROBIOLOGY | - |
dc.subject | 2,2 '-dipyridyl | - |
dc.subject | Trichomonas vaginalis | - |
dc.subject | Candida albicans | - |
dc.subject | Gardnerella vaginalis | - |
dc.title | In vitro activities of 2,2 '-dipyridyl against Trichomonas vaginalis, Candida albicans, and Gardnerella vaginalis | - |
dc.type | Article | - |
dc.relation.issue | 1 | - |
dc.relation.volume | 11 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 124 | - |
dc.relation.lastpage | 130 | - |
dc.relation.journaltitle | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.identifier.wosid | WOS:000167320200021 | - |
dc.author.google | Ryu, JS | - |
dc.author.google | Min, DY | - |
dc.author.google | Kim, MC | - |
dc.author.google | Kim, NS | - |
dc.author.google | Shin, MH | - |
dc.date.modifydate | 20200911081002 | - |