Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 史惠淳 | - |
dc.creator | 史惠淳 | - |
dc.date.accessioned | 2016-08-26T11:08:56Z | - |
dc.date.available | 2016-08-26T11:08:56Z | - |
dc.date.issued | 1973 | - |
dc.identifier.other | OAK-000000058049 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/203047 | - |
dc.identifier.uri | http://dcollection.ewha.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000058049 | - |
dc.description.abstract | 2,2'-Methylene bis (3,4,6,-trichloroacetoxy) benzene had teen synthesized from hexachlorophene. Eleven new derivatives of 2,2'_Methylene bis (3,4,6,-trichloroacetoxy benzene) were synthesized by Mannich's reaction. Effects of thenew compounds on 15-strains of becterias and yeasts were examinedboth paper disk methed and tube dilution method.Among them, compounds of benzylamine and p-toluidina revealed most offective antimlcroblal activity to Bacillus subtilis and Psevdomonas ovalis. The mintmal inhibitory concentration of 2,2'_Methylene bis 3,4,6,trichloro (-p-toluidinopropionoxy)benzene and 2,2'-Methylene bis3.4,6,-trichloro-benzylaminoprooionoxy) benzene on Bacillus subilis are 1ug/ml ana that of Rseudomonas ovalis are 2ug/ml, lug/ml by tube dilution method. Minimal inhibitory concentration(m.i.c.)of p-toluidinea,m,pound inhibited the growht and production of amylase and oroteaseactivitf of logarithmic Phase cells of Bacillus subtilis. | - |
dc.description.tableofcontents | 목차 = 0 -ABSTRACT- = 0 제Ⅰ장 2,2'-Methylene bis(3,4,6-trichloroacetoxy benzene)유도체의 합성 및 항균성 = 1 Ⅰ. 서론 = 1 Ⅱ. 재료 및 실험방법 = 3 (1) 항균성 검정균주 = 3 (2) 항균성 검정배지 = 3 (3) 항균성 검정시료 = 4 (4) 합성법 = 5 (5) 항균성 검정법 = 7 Ⅲ. 결과 및 고찰 = 9 (1) 2,2'-Methylene bis(3,4,6-trichloroacetoxy benzene)유도체의 합성 = 9 (2) 항균성 = 14 (3) 최저생육 저해 농도(M.I.C) = 15 Ⅳ. 요약 = 19 제2장 2,2'-Methylene bis[3,4,6-trichloro(β-p-toluidino propionoxy)benzene]이 Bacillus Subtilis의 생합성에 미치는 영향 = 20 Ⅰ. 서론 = 20 Ⅱ. 재료 및 실험방법 = 21 (1) 재료 = 21 (2) Amylase 활성측정법 = 21 (3) Protease 활성측정법 = 22 (4) 균체량 측정법 = 23 Ⅲ. 결과 = 24 (1) 2,2'-Methylene bis[3,4,6-trichloro(β-p-toluidinopropionoxy)benzene]가 균체의 생합성에 미치는 영향 = 24 (2) 균체외 protease 생합성에 미치는 영향 = 28 (3) 균체외 Amylase 생합성에 미치는 영향 = 31 Ⅳ. 고찰 = 36 Ⅴ. 요약 = 38 참고문헌 = 40 | - |
dc.format | application/pdf | - |
dc.format.extent | 1307465 bytes | - |
dc.language | kor | - |
dc.publisher | 이화여자대학교 대학원 | - |
dc.title | 2, 2'-Methylene bis(3, 4, 6-trichloroacetoxy benzene) 유도체의 항균성에 관한 연구 | - |
dc.type | Master's Thesis | - |
dc.format.page | 41 p. | - |
dc.identifier.thesisdegree | Master | - |
dc.identifier.major | 대학원 약학과 | - |
dc.date.awarded | 1973. 2 | - |